More than 100 years ago, German physician Paul Ehrlich first proposed the concept of
selectively delivering “magic bullets” to tumors through targeting agents. The targeting …

Photodynamic therapy (PDT) has attracted great attention as an alternative tumor treatment
method. Unfortunately, it suffers from some limitations like poor targeting capability and …

ABSTRACT Introduction: Hyaluronan (HA), a natural polysaccharide, is produced in large
amounts by the human body. Since its receptor CD44 is highly expressed in many types of …

The precise assessment of vascular heterogeneity in brain tumors is vital for diagnosing,
grading, predicting progression, and guiding treatment decisions. However, currently, there …

Active-targeted cancer imaging and therapy of glioma has attracted much attention in
theranostic nanomedicine. As a promising tumor-targeting ligand, holo-transferrin (holo-Tf) …

To achieve lung cancer gene therapy, nanocarriers decorated with different ligands were
used. Surface decoration and nanoparticulate system will assist in targeting the gene to …

In this paper, a CD44-targeted and redox-responsive drug delivery system based on
mesoporous silica nanoparticles (MSNs) was synthesized by conjugating tumor-shedable …

The precise mapping of collateral circulation and ischemic penumbra is crucial for
diagnosing and treating acute ischemic stroke (AIS). Unfortunately, there exists a significant …

Abstract Development of intelligent and multifunctional nanoparticle for the diagnosis and
treatment of cancer has drawn great attention recently. In this work, we design a smart two …

We report on the synthesis and characterization of a composite nanostructure based on the
coupling of cerium fluoride (CeF 3) and zinc oxide (ZnO) for applications in self-lighted …