The syntheses of almost all N-heterocycles have now been successfully performed under
microwave irradiation and have provided significant improvements in the reaction time and …

The development of new strategies for the synthesis of small-sized heterocycles has
remained a highly attractive but challenging proposition. An overview of the application of …

Combretastatin A-4 (CA-4) in phosphate and serine pro-drug forms is under phase II clinical
trials. With our interest of discovering CA-4 inspired new chemical entities, a novel series of …

A series of 2-aminothiazoles was synthesized based on a HTS scaffold from a whole-cell
screen against Mycobacterium tuberculosis (Mtb). The SAR shows the central thiazole …

A library of 112 4 (5)-aryl-2-amino-1 H-imidazoles, 4, 5-diphenyl-2-amino-1 H-imidazoles,
and N 1-substituted 4 (5)-phenyl-2-aminoimidazoles was synthesized and tested for the …

Imidazo [1, 2-a] pyrimidine has been receiving significant attention in the synthetic chemistry
community through different chemosynthetic methodologies viz., multicomponent reactions …

Imidazole, an important azole heterocycle, having biological and medicinal properties
prompted various research groups to develop different synthetic routes to this heterocycle …

Imidazole ring is an important scaffold in many biologically important molecules. Many
methods have been reported for the synthesis of imidazoles. Several methods of generating …

A new strategy in the design of aminergic GPCR ligands is proposed–the use of aromatic,
heterocyclic basic moieties in place of the evergreen piperazine or alicyclic and aliphatic …

Abstract A library of 80 1-substituted 2-hydroxy-2-aryl-2, 3-dihydro-imidazo [1, 2-a]
pyrimidinium salts and 54 2N-substituted 4 (5)-aryl-2-amino-1H-imidazoles was synthesized …