Frailty in advanced liver disease

R Laube, H Wang, L Park, JK Heyman… - Liver …, 2018 - Wiley Online Library
Prognostication of patients with cirrhosis is complex, depending on more than just the
severity of liver disease. Scores such as the model for end‐stage liver disease (MELD) and …

Impact of immune-modulatory drugs on regulatory T cell

A Furukawa, SA Wisel, Q Tang - Transplantation, 2016 - journals.lww.com
Immunosuppression strategies that selectively inhibit effector T cells while preserving and
even enhancing CD4+FOXP3+ regulatory T cells (Treg) permit immune self-regulation and …

[HTML][HTML] Report from the American Society of Transplantation on frailty in solid organ transplantation

J Kobashigawa, D Dadhania, S Bhorade… - American Journal of …, 2019 - Elsevier
A consensus conference on frailty in kidney, liver, heart, and lung transplantation sponsored
by the American Society of Transplantation (AST) and endorsed by the American Society of …

[HTML][HTML] Pre-kidney transplant lower extremity impairment and post-kidney transplant mortality

AJ Nastasi, MA McAdams-DeMarco, J Schrack… - American Journal of …, 2018 - Elsevier
Prediction models for post-kidney transplantation mortality have had limited success (C-
statistics≤ 0.70). Adding objective measures of potentially modifiable factors may improve …

Transplant centers that assess frailty as part of clinical practice have better outcomes

X Chen, Y Liu, V Thompson, NM Chu, EA King… - BMC geriatrics, 2022 - Springer
Background Frailty predicts adverse post-kidney transplant (KT) outcomes, yet the impact of
frailty assessment on center-level outcomes remains unclear. We sought to test whether …

A comparison of different frailty scores and impact of frailty on outcome in patients with cirrhosis

S Singh, S Taneja, P Tandon, A Bansal, U Gorsi… - Journal of Clinical and …, 2022 - Elsevier
Background & aims There is no “gold standard” tool for the assessment of frailty in cirrhosis.
This study compares Liver Frailty Index (LFI), Short Physical Performance Battery (SPPB) …

Frailty assessment as part of transplant listing: yes, no or maybe?

MA McAdams-DeMarco, AK Thind… - Clinical Kidney …, 2023 - academic.oup.com
Frailty, characterized by a decreased physiological reserve and an increased vulnerability to
stressors, is common among kidney transplant (KT) candidates and recipients. In this review …

Frailty and sarcopenia in older patients receiving kidney transplantation

I Gandolfini, G Regolisti, A Bazzocchi… - Frontiers in …, 2019 - frontiersin.org
Kidney transplantation is the treatment of choice for most of the patients with end-stage renal
disease (ESRD). It improves quality of life, life expectancy, and has a lower financial burden …

Frailty in the end-stage lung disease or heart failure patient: implications for the perioperative transplant clinician

BA Bottiger, A Nicoara, LD Snyder… - Journal of cardiothoracic …, 2019 - Elsevier
The syndrome of frailty for patients undergoing heart or lung transplantation has been a
recent focus for perioperative clinicians because of its association with postoperative …

Frailty in children with liver disease: a prospective multicenter study

E Lurz, C Quammie, M Englesbe, EM Alonso… - The Journal of …, 2018 - Elsevier
Objective To assess frailty, a measure of physiologic declines in multiple organ systems, in
children with chronic liver disease using a novel pediatric frailty tool. Study design We …