Non-steroidal anti-inflammatory drugs (NSAIDs) are the competitive inhibitors of
cyclooxygenase (COX), the enzyme which mediates the bioconversion of arachidonic acid …

Imidazole nucleus is a constituent of many bioactive heterocyclic compounds that are of
wide interest because of their diverse biological and clinical applications. This created …

A series of substituted 4-(2, 6-dichlorobenzyloxy) phenyl thiazole, oxazole and imidazole
derivatives were synthesized. The derivatives were screened for in vitro anti-tubercular …

The non-steroidal anti-inflammatory drugs (NSAIDs) are diverse group of compounds used
for the treatment of inflammation, since the introduction of acetylsalicylic acid in 1899 …

A series of synthesized compounds based on pyrazole and imidazole skeletons prepared by
palladium catalysts via a one-pot reaction was screened to determine their inhibitory …

Introduction: In the past, clinical studies had demonstrated that aspirin and NSAIDs reduce
the risk of colorectal cancer. After the discovery of selective prostaglandin-endoperoxide …

A systematic exploration of thiophilic ability of o-iodoxybenzoic acid (IBX) for oxidative
desulfurization to trigger domino reactions leading to new methodologies for synthesis of …

An expedient and efficient approach for the synthesis of structurally diverse carbonyl-
bridged bisheterocycles has been developed via a palladium-catalyzed four-component …

Background: Bacterial infections are a growing problem worldwide causing morbidity and
mortality mainly in developing countries. Moreover, the increased number of …

Abstract In the present study, 2, 6-diflurobenzohydrazide 1 and 4-fluorophenylisothiocyanate
were used as the starting materials to synthesize 5-(2, 6-diflurophenyl)-N 3-(4-fluorophenyl) …