Mammalian prion biology: one century of evolving concepts
A Aguzzi, M Polymenidou - Cell, 2004 - cell.com
Prions have been responsible for an entire century of tragic episodes. Fifty years ago, kuru
decimated the population of Papua New Guinea. Then, iatrogenic transmission of prions …
decimated the population of Papua New Guinea. Then, iatrogenic transmission of prions …
Transmissible spongiform encephalopathies
SJ Collins, VA Lawson, CL Masters - The Lancet, 2004 - thelancet.com
Nosologically, transmissible spongiform encephalopathies (TSE or prion diseases) should
be grouped with other neurodegenerative disorders such as Alzheimer's and Parkinson's …
be grouped with other neurodegenerative disorders such as Alzheimer's and Parkinson's …
[图书][B] Epidemiologic methods: studying the occurrence of illness
TD Koepsell, NS Weiss - 2014 - books.google.com
This second edition of Epidemiologic Methods offers a rigorous introduction to the concepts
and tools of epidemiologic research. Aimed chiefly at future epidemiologists, the book offers …
and tools of epidemiologic research. Aimed chiefly at future epidemiologists, the book offers …
Mortality from Creutzfeldt–Jakob disease and related disorders in Europe, Australia, and Canada
Background: An international study of the epidemiologic characteristics of Creutzfeldt–Jakob
disease (CJD) was established in 1993 and included national registries in France, Germany …
disease (CJD) was established in 1993 and included national registries in France, Germany …
Molecular classification of sporadic Creutzfeldt–Jakob disease
AF Hill, S Joiner, JDF Wadsworth, KCL Sidle, JE Bell… - Brain, 2003 - academic.oup.com
According to the protein‐only hypothesis of prion propagation, an abnormal isoform
(designated PrPSc) of the cellular prion protein (PrPC) is the principal or sole component of …
(designated PrPSc) of the cellular prion protein (PrPC) is the principal or sole component of …
[HTML][HTML] BSE prions propagate as either variant CJD‐like or sporadic CJD‐like prion strains in transgenic mice expressing human prion protein
EA Asante, JM Linehan, M Desbruslais, S Joiner… - The EMBO …, 2002 - embopress.org
Abstract Variant Creutzfeldt–Jakob disease (vCJD) has been recognized to date only in
individuals homozygous for methionine at PRNP codon 129. Here we show that transgenic …
individuals homozygous for methionine at PRNP codon 129. Here we show that transgenic …
Extraneural pathologic prion protein in sporadic Creutzfeldt–Jakob disease
Background In patients with sporadic Creutzfeldt–Jakob disease, pathologic disease-
associated prion protein (PrPSc) has been identified only in the central nervous system and …
associated prion protein (PrPSc) has been identified only in the central nervous system and …
Prospective 10-year surveillance of human prion diseases in Japan
I Nozaki, T Hamaguchi, N Sanjo, M Noguchi-Shinohara… - Brain, 2010 - academic.oup.com
We analysed the epidemiological data and clinical features of patients with prion diseases
that had been registered by the Creutzfeldt-Jakob Disease Surveillance Committee, Japan …
that had been registered by the Creutzfeldt-Jakob Disease Surveillance Committee, Japan …
Validation and utilization of amended diagnostic criteria in Creutzfeldt-Jakob disease surveillance
Objective To validate an amended protocol for clinical diagnosis of sporadic Creutzfeldt-
Jakob disease (sCJD) including real-time quaking-induced conversion (RT-QuIC) and to …
Jakob disease (sCJD) including real-time quaking-induced conversion (RT-QuIC) and to …
Coexistence of multiple PrPSc types in individuals with Creutzfeldt-Jakob disease
M Polymenidou, K Stoeck, M Glatzel, M Vey… - The Lancet …, 2005 - thelancet.com
Background The molecular typing of sporadic Creutzfeldt-Jakob disease (CJD) is based on
the size and glycoform ratio of protease-resistant prion protein (PrP Sc), and on PRNP …
the size and glycoform ratio of protease-resistant prion protein (PrP Sc), and on PRNP …