The adult quiescent blood–brain barrier (BBB), a structure organised by endothelial cells
through interactions with pericytes, astrocytes, neurons and microglia in the neurovascular …

Mapping tissue microstructure with MRI holds great promise as a noninvasive window into
tissue organization at the cellular level. Having originated within the realm of diffusion NMR …

Alzheimer's disease (AD) is the most common cause of dementia and is characterized by
progressive neurodegeneration and cognitive decline. Understanding the pathophysiology …

Cerebral small vessel disease (cSVD) comprises pathological processes of the small
vessels in the brain that may manifest clinically as stroke, cognitive impairment, dementia, or …

OBJECTIVE. This and its companion article address the 10 most frequently asked questions
that radiologists face when planning, performing, processing, and interpreting different MR …

The blood–brain barrier (BBB) is the interface between the central nervous system and
systemic circulation. It tightly regulates what enters and is removed from the brain …

Purpose To present a novel MR pulse sequence and modeling algorithm to quantify the
water exchange rate (kw) across the blood–brain barrier (BBB) without contrast, and to …

There is currently a lack of non-invasive tools to assess water transport in healthy and
pathological brain tissue. Aquaporin-4 (AQP4) water channels are central to many water …

Purpose To assess the reproducibility and the distribution of intravoxel incoherent motion
(IVIM) and diffusion-tensor (DT) imaging parameters in healthy renal cortex and medulla at …

Blood-brain barrier (BBB) separates the systemic circulation and the brain, regulating
transport of most molecules to protect the brain microenvironment. Multiple structural and …