Two distinct evolutionary conserved neural degeneration pathways characterized in a colonial chordate

C Anselmi, M Kowarsky, F Gasparini… - Proceedings of the …, 2022 - National Acad Sciences
Colonial tunicates are marine organisms that possess multiple brains simultaneously during
their colonial phase. While the cyclical processes of neurogenesis and neurodegeneration …

Botryllus schlosseri, an emerging model for the study of aging, stem cells, and mechanisms of regeneration

A Voskoboynik, IL Weissman - Invertebrate reproduction & …, 2015 - Taylor & Francis
The decline of tissue regenerative potential with the loss of stem cell function is a hallmark of
mammalian aging. We study Botryllus schlosseri, a colonial chordate which exhibits robust …

HES1 is required for mouse fetal hematopoiesis

AZ Zhu, Z Ma, EV Wolff, Z Lin, ZJ Gao, X Li… - Stem Cell Research & …, 2024 - Springer
Background Hematopoiesis in mammal is a complex and highly regulated process in which
hematopoietic stem cells (HSCs) give rise to all types of differentiated blood cells. Previous …

The Wave2 scaffold Hem-1 is required for transition of fetal liver hematopoiesis to bone marrow

L Shao, J Chang, W Feng, X Wang… - Nature …, 2018 - nature.com
The transition of hematopoiesis from the fetal liver (FL) to the bone marrow (BM) is
incompletely characterized. We demonstrate that the Wiskott–Aldrich syndrome verprolin …

Stage-specific changes in the Krebs cycle network regulate human erythroid differentiation

M Romano - 2018 - theses.hal.science
Hematopoiesis is the process whereby hematopoietic stem cells (HSCs) proliferate and
differentiate to all blood cell lineages. While HSC commitment is known to be regulated by …