Antibacterial peptides: basic facts and emerging concepts

HG Boman - Journal of internal medicine, 2003 - Wiley Online Library
Boman HG (Microbiology and Tumor Biology Center, Karolinska Institutet, Stockholm,
Sweden). Antibacterial peptides: basic facts and emerging concepts (Review). J Intern Med …

Animal antimicrobial peptides: an overview

D Andreu, L Rivas - Peptide Science, 1998 - Wiley Online Library
Antibiotic peptides are a key component of the innate immune systems of most multicellular
organisms. Despite broad divergences in sequence and taxonomy, most antibiotic peptides …

An antimicrobial activity of cytolytic T cells mediated by granulysin

S Stenger, DA Hanson, R Teitelbaum, P Dewan… - Science, 1998 - science.org
Cytolytic T lymphocytes (CTLs) kill intracellular pathogens by a granule-dependent
mechanism. Granulysin, a protein found in granules of CTLs, reduced the viability of a broad …

The human antimicrobial and chemotactic peptides LL-37 and α-defensins are expressed by specific lymphocyte and monocyte populations

B Agerberth, J Charo, J Werr, B Olsson… - Blood, The Journal …, 2000 - ashpublications.org
We identified antibacterial components in human T and natural killer (NK) cells by using
freshly isolated lymphocytes enriched for T and NK cells as starting material. After growing …

Function of surfactant proteins B and C

TE Weaver, JJ Conkright - Annual review of physiology, 2001 - annualreviews.org
▪ Abstract SP-B is the only surfactant-associated protein absolutely required for postnatal
lung function and survival. Complete deficiency of SP-B in mice and humans results in …

Differential effects of cytolytic T cell subsets on intracellular infection

S Stenger, RJ Mazzaccaro, K Uyemura, S Cho… - Science, 1997 - science.org
In analyzing mechanisms of protection against intracellular infections, a series of human
CD1-restricted T cell lines of two distinct phenotypes were derived. Both CD4− CD8−(double …

The human cationic antimicrobial protein (hCAP18), a peptide antibiotic, is widely expressed in human squamous epithelia and colocalizes with interleukin-6

M Frohm Nilsson, B Sandstedt, O Sørensen… - Infection and …, 1999 - Am Soc Microbiol
Peptide antibiotics are widespread in nature and, by providing a rapid first line of defense,
may be key players in the innate immune system. Although epithelia are the main barriers …

Antimicrobial activity and stability to proteolysis of small linear cationic peptides with D‐amino acid substitutions

K Hamamoto, Y Kida, Y Zhang… - Microbiology and …, 2002 - Wiley Online Library
Antimicrobial peptides contribute to innate host defense against a number of bacteria and
fungal pathogens. Some of antimicrobial synthetic peptides were systemically administered …

Novel CDNF/MANF family of neurotrophic factors

P Lindholm, M Saarma - Developmental neurobiology, 2010 - Wiley Online Library
Current therapeutic interventions for neurodegenerative diseases alleviate only disease
symptoms, while treatments that could stop or reverse actual degenerative processes are …

Molecular structures and interactions of pulmonary surfactant components

J Johansson, T Curstedt - European journal of biochemistry, 1997 - Wiley Online Library
The dominating functional property of pulmonary surfactant is to reduce the surface tension
at the alveolar air/liquid interface, and thereby prevent the lungs from collapsing at the end …