Pitfalls in breast pathology

C Quinn, A Maguire, E Rakha - Histopathology, 2023 - Wiley Online Library
Accurate pathological diagnosis is the cornerstone of optimal clinical management for
patients with breast disease. As non‐operative diagnosis has now become the standard of …

Avoiding “false positive” and “false negative” immunohistochemical results in breast pathology

Z Li, DJ Dabbs - Pathobiology, 2022 - karger.com
Immunohistochemistry (IHC) plays an important role in the evaluation of breast pathology
specimens to provide both diagnostic and prognostic/therapeutic information. Although most …

TRPS1 expression in cytokeratin 5 expressing triple negative breast cancers, its value as a marker of breast origin

S Almási, L Kuthi, A Sejben, A Vörös, Á Nagy… - Virchows Archiv, 2023 - Springer
The lack of oestrogen receptor, progesterone receptor and human epidermal growth factor
receptor-2 expression in breast cancer (BC) is the basis for the categorization of the tumour …

The utility of SOX10 immunohistochemical staining in breast pathology: staining of myoepithelial cells, distinction of atypical ductal hyperplasia from usual ductal …

R Rammal, K Goel, E Elishaev… - American Journal of …, 2022 - academic.oup.com
Objectives SOX10 expression helps identify melanocytic lesions. Over time, novel uses have
been identified, such as expression in triple-negative breast cancer (TNBC). We evaluated …

Immunohistochemical Profile of Triple-Negative Breast Cancers: SOX10 and AR Dual Negative Tumors Have Worse Outcomes

R Rammal, K Goel, SA Motanagh, GJ Carter, BZ Clark… - Modern Pathology, 2024 - Elsevier
Triple-negative breast cancer (TNBC) refers to an estrogen receptor–negative, progesterone
receptor–negative, and HER2-negative breast cancer. Although accepted as a clinically …

A cutting-edge investigation of the multifaceted role of SOX family genes in cancer pathogenesis through the modulation of various signaling pathways

SA Jasim, SH Farhan, I Ahmad, A Hjazi… - Functional & Integrative …, 2025 - Springer
This detailed study examines the complex role of the SOX family in various tumorigenic
contexts, offering insights into how these transcription factors function in cancer. As the study …

Clinicopathologic and molecular characteristics of and diagnostic dilemmas in invasive breast carcinoma with choriocarcinomatous pattern apropos a new case: A …

SY Jun, N Yoon, S An, YJ Kang, CS Park - Pathobiology, 2022 - karger.com
Background: Invasive breast carcinoma with a choriocarcinomatous pattern (IBC-CP) is
extremely rare, and its molecular basis is yet unclear. The choriocarcinomatous pattern is …

Combination of GATA3, SOX-10, and PAX8 in a comprehensive panel to diagnose breast cancer metastases

K Na, HY Woo, SI Do, SW Kim - in vivo, 2022 - iv.iiarjournals.org
Background/Aim: It can be difficult to establish the origin of a tumor in metastatic breast
cancer (MBC), especially with triple-negative breast cancer (TNBC) or high-grade features …

TRPS1 expression in breast angiosarcoma

T Pancsa, B Pósfai, A Schubert, S Almási, E Papp… - Virchows Archiv, 2024 - Springer
Angiosarcoma (AS) of the breast, a rare mesenchymal neoplasm, exhibits distinct forms
based on etiological and genetic features. While cases with typical clinical presentation and …

Breast lesions with myoepithelial phenotype

MP Foschini, R Nishimura, VP Fabbri, Z Varga… - …, 2023 - Wiley Online Library
Myoepithelial cells (MECs) constitute a continuous layer of cells surrounding the breast
glands, localised between the epithelial cells (ECs) and the basal membrane. MECs play …