The endoplasmic reticulum (ER), an organelle present in various eukaryotic cells, is
responsible for intracellular protein synthesis, post-translational modification, and folding …

Chemotherapeutics have been recommended as the standard protocol for inoperable
patients with triple-negative breast cancer (TNBC) at advanced stage, yet limited success …

Cancer is a significant cause of death around the world, and for many varieties, treatment is
not successful. Therefore, there is a need for the development of innovative, efficacious, and …

Lysosomal acid lipase (LAL) is a lysosomal enzyme essential for the degradation of
cholesteryl esters through the endocytic pathway. Deficiency of the LAL enzyme encoded by …

Type I photodynamic therapy (PDT) is attracting increasing interest as an effective solution to
the poor prognosis of patients with hypoxic tumors. The development of functional type I …

Background Breast cancer is the most frequently diagnosed cancer and a leading cause of
cancer-related death in women. Endoplasmic reticulum stress (ERS) plays a crucial role in …

Hepatocellular carcinoma (HCC) is among the most aggressive and lethal human tumors.
Many functional studies have demonstrated the role of non-coding RNAs (ncRNA) …

In situ vaccination can elicit systemic antitumor immunity to potentiate immune checkpoint
blockade (ICB) in poorly immunogenic tumors. Herein, an immunogenic cell death (ICD) …

Background Breast cancer (BC) is the primary cause of cancer mortality. Herein, we aimed
to establish and verify a prognostic model consisting of endoplasmic reticulum stress and …

Simple Summary In the United States, ovarian cancer (OCa) is the most lethal of all
gynecologic malignancies. Survival rates for OCa with clinically localized disease have …