Glycosaminoglycans (GAGs) including chondroitin sulfate, dermatan sulfate, and heparan
sulfate are covalently attached to specific core proteins to form proteoglycans, which are …

Sažetak Carbohydrate sulfotransferases (CHST) catalyse the biosynthesis of proteoglycans
that enable physical interactions and signalling between different neighbouring cells in …

Purpose Congenital clubfoot is a serious birth defect that affects nearly 0.1% of all births.
Though there is strong evidence for a genetic basis of isolated clubfoot, aside from a handful …

Nutrient sulfate is essential for numerous physiological functions in mammalian growth and
development. Accordingly, disruptions to any of the molecular processes that maintain the …

Background To study the role of single nucleotide variants (SNVs) of genes related to
preeclampsia in Pakistani pregnant women. Methods After ethical approval and getting …

Objectives This study investigated the association of MSX1 gene variants rs3821949 and
rs12532 with nonsyndromic cleft lip and/or palate (NSCL/P) in the Pakistani population …

Genetic skeletal disorders (GSDs) constitute a heterogeneous, rare and a distinctive group
of rare bone growth disorders, leading to abnormal size and shape of the skeleton …

This study aimed to analyze the serum and salivary levels of copper (Cu), zinc (Zn), iron
(Fe), chromium (Cr), manganese (Mn) and the Cu/Zn ratio and investigate the association …

Biallelic variants in CHST3 gene result in congenital dislocation of large joints, club feet,
short stature, rhizomelia, kypho‐scoliosis, platyspondyly, epiphyseal dysplasia, flared …

Sulfation is an essential posttranslational modification that involves the covalent attachment
of sulfate groups to the hydroxyl or amine group of the acceptor molecule. This modification …