Mutations in PRKN cause the second most common genetic form of Parkinson's disease
(PD)—a debilitating movement disorder that is on the rise due to population aging in the …

Glucose metabolism is essential for the maintenance and function of the central nervous
system. Although the brain constitutes only 2% of the body weight, it consumes …

Many studies have reported metabolomic analysis of different bio-specimens from
Parkinson's disease (PD) patients. However, inconsistencies in reported metabolite …

Despite many years of research into the complex neurobiology of Parkinson's disease, the
precise aetiology cannot be pinpointed down to one causative agent but rather a multitude …

Mitochondrial DNA (mtDNA) variants considerably affect diabetes mellitus by disturbing
mitochondrial function, energy metabolism, oxidative stress response, and even insulin …

Alterations in many metabolites and biochemical pathways have been described in
Parkinson's Disease (PD). However, only a small fraction of these have been replicated in …

Many studies have reported metabolomic analysis of different bio-specimens from
Parkinson's disease patients. However, inconsistencies in reported metabolite concentration …

Background: Parkinson's disease (PD) is a progressive neurodegenerative disorder.
Increasing evidence suggests that PD patients have alterations in glucose metabolism and …