Transplantation is unusual in that T cells can recognize alloantigen by at least two distinct
pathways: as intact MHC alloantigen on the surface of donor cells via the direct pathway; …

Damage-associated molecular patterns (DAMPs) are endogenous molecules released by
cells in response to injury or stress, recognized by host pattern recognition receptors that …

T cells differentiate into functionally distinct states upon antigen encounter. These states are
delineated by different cell surface markers for murine and human T cells, which hamper …

Recent cross-sectional studies suggest an important role for transitional B lymphocytes
(CD19+ CD24hiCD38hi) in promoting transplant tolerance, and protecting from late antibody …

Innate lymphoid cells (ILCs) are highly plastic and predominantly mucosal tissue-resident
cells that contribute to both homeostasis and inflammation depending on the …

Background The mechanisms regulating CD8+ T cell migration to nonlymphoid tissue
during inflammation have not been fully elucidated, and the migratory properties of effector …

Abstract Persistent ATG‐induced CD4+ T cell lymphopenia is associated with serious
clinical complications. We tested the hypothesis that ATG induces accelerated immune …

Background Identifying biomarkers to predict kidney transplant failure and to define new
therapeutic targets requires more comprehensive understanding of the immune response to …

Introduction Systemic lupus erythematosus (SLE) is an autoimmune disease in which
circulating immune complexes can cause different types of glomerulonephritis, according to …

T cells play a key role in determining allograft function by mediating allogeneic immune
responses to cause rejection, and recent work pointed their role in mediating tolerance in …