Antibacterial and antioxidant activities for natural and synthetic dual-active compounds

G Martelli, D Giacomini - European Journal of Medicinal Chemistry, 2018 - Elsevier
Antimicrobial resistance is widely recognized as a grave threat to global health in the 21st
century, since the past decades have seen a dramatic increase in human-pathogenic …

4-Quinolone hybrids and their antibacterial activities

YQ Hu, S Zhang, Z Xu, ZS Lv, ML Liu… - European Journal of …, 2017 - Elsevier
The emergence and wide-spread of drug-resistant bacteria including multi-drug resistant
and pan-drug resistant pathogens which are associated with considerable mortality …

4-Quinolone derivatives and their activities against Gram positive pathogens

GF Zhang, S Zhang, B Pan, X Liu, LS Feng - European Journal of Medicinal …, 2018 - Elsevier
Gram-positive bacteria are responsible for a broad range of infectious diseases, and the
emergency and wide spread of drug-resistant Gram-positive pathogens including MRSA …

Synthesis of new 1, 2, 4-triazole compounds containing Schiff and Mannich bases (morpholine) with antioxidant and antimicrobial activities

Y Ünver, S Deniz, F Çelik, Z Akar, M Küçük… - Journal of Enzyme …, 2016 - Taylor & Francis
Compound 2 was synthesized by reacting CS2/KOH with compound 1. The treatment of
compound 2 with hydrazine hydrate produced compound 3. Then, compound 3 was …

Synthesis and antibacterial activity of pyridinium-tailored 2, 5-substituted-1, 3, 4-oxadiazole thioether/sulfoxide/sulfone derivatives

PY Wang, L Zhou, J Zhou, ZB Wu, W Xue… - Bioorganic & Medicinal …, 2016 - Elsevier
By introducing the pyridinium group into 2, 5-substituted-1, 3, 4-oxadiazole, a series of
pyridinium-tailored 2, 5-substituted-1, 3, 4-oxadiazole thioether/sulfoxide/sulfone derivatives …

Design, synthesis, metal chelation potential and biological evaluation of pyridine chalcones as multi-target-directed ligands against Alzheimer's disease

G Dixit, A Prabhu - Journal of Molecular Structure, 2023 - Elsevier
Abstract Two sets of 1-phenyl-3-(pyridinyl) prop‑2-en-1-one analogs, 7a-d and 8a-d were
designed by the incorporation of pyridine and chalcone privileged scaffolds with the …

Novel 2-amino-4-aryl-6-pyridopyrimidines and N-alkyl derivatives: Synthesis, characterization and investigation of anticancer, antibacterial activities and DNA/BSA …

N Kahriman, K Peker, V Serdaroğlu, A Aydın, A Usta… - Bioorganic …, 2020 - Elsevier
A series of new 2-amino-4-aryl-6-pyridopyrimidines, and their N-alkyl bromide derivatives
were designed and synthesized by employing methyl substituted azachalcones. These …

An efficient one-pot approach for the regio-and diastereoselective synthesis of trans-dihydrofuran derivatives: cytotoxicity and DNA-binding studies

Y Tangella, KL Manasa, VL Nayak, M Sathish… - Organic & …, 2017 - pubs.rsc.org
An operationally facile and high yielding one-pot, three-component protocol has been
developed for the preparation of selectively trans-2, 3-dihydrofuro [3, 2-c] coumarins and …

A mononuclear Co (II) complex: Crystal structure, thermal behavior, optical properties and biological activities

S Dgachi, F Rahmouni, A Soran, M Saoudi… - Journal of Molecular …, 2021 - Elsevier
A new mononuclear cobalt hybrid material (C 6 H 9 N 2) 2 [CoCl 4] was prepared using slow
evaporation technique at room temperature. The X-ray diffraction analysis revealed that the …

4‐Quinolone Derivatives and Their Activities Against Gram‐negative Pathogens

D Jiang - Journal of Heterocyclic Chemistry, 2018 - Wiley Online Library
Gram‐negative pathogens represent a significant global health threat, while the emergency
and widespread of drug resistance make the situation even worse. As “privileged building …