Nanoparticles can be near infrared (NIR)-fluorescent (eg, gold nanoparticles, quantum dots
or carbon nanotubes) or can have magnetic properties (eg, iron oxide nanoparticles). These …

Castration-resistant prostate cancer remains incurable and a major cause of mortality
worldwide. The absence of effective therapeutic approaches for advanced prostate cancer …

The conjugation of peptides to gold nanoparticles (AuNPs) produces biocompatible and
stable multimeric systems with target‐specific molecular recognition. Peptides based on the …

Mammalian bombesin (Bn) receptors comprise 3 subtypes: BB 1, BB 2, BB 3 (nomenclature
recommended by the NC-IUPHAR Subcommittee on bombesin receptors,[109]). BB 1 and …

The gastrin-releasing peptide receptor (GRP-r) is overexpressed in breast and prostate
cancer, and Lys3-bombesin is a peptide that binds with high affinity to the GRP-r. HIV Tat (49 …

Gastrin-releasing peptide (GRP) receptors are over-expressed in various human tumor
including breast and prostate which can be targeted with bombesin for diagnosis and …

We evaluated and compared a new bombesin analog [Tyr–Gly 5, Nle 14]-BBN (6–14)
conjugated to DOTA or DTPA and radiolabeled with In-111 in low and high GRPR …

The aim of the present work was to obtain stabilized high specific activity (HSA) 111In-
labeled bombesin conjugates for preclinical evaluations. Parameters influencing the kinetics …

Mammalian bombesin (Bn) receptors comprise 3 subtypes: BB 1, BB 2, BB 3 (nomenclature
recommended by the NC-IUPHAR Subcommittee on bombesin receptors,[115]). BB 1 and …

Bombesin is a 14-amino-acid peptide having the ability to specifically bind gastrin releasing
peptide receptors (GRPR) which show over-expression in many types of cancer cells …