Bromination is one of the most important transformations in organic synthesis and can be
carried out using bromine and many other bromo compounds. Use of molecular bromine in …

Heterocycles are an extraordinarily important class of compounds, making up more than half
of all known organic compounds. Heterocycles are present in a wide variety of drugs, most …

The one-pot three-component reaction for the synthesis of pyran annulated heterocycles is
reported by condensing aromatic aldehydes, ethyl cyanoacetate, or malononitrile and C–H …

Nitrogen-containing compounds are ubiquitous in nature and many of them are biologically
active (eg, 1, 2, 3, 4; Fig. 1). The nitrogen-containing units of these molecules play important …

A simple, straightforward, and highly efficient diastereoselective multicomponent one-pot
synthesis of a series of pharmaceutically interesting functionalized piperidine derivatives …

Tetrabutylammonium tribromide (TBATB) has been found to be an efficient catalyst for the
one-pot synthesis of highly substituted piperidines through a combination of 1, 3-dicarbonyl …

A highly atom-economic one-pot synthesis of functionalized tetrahydropyridines by a
multicomponent condensation reaction of β-keto ester, two equivalents of aromatic …

The advent of multicomponent reactions in the synthesis of heterocycles and their ever
burgeoning applications in drug development, materials chemistry, and catalysis, have …

Efficient one-pot synthesis of functionalized piperidine scaffolds via ZrOCl2·8H2O catalyzed
tandem reactions of aromatic aldehydes with amines and acetoacetic esters - ScienceDirect …

Abstract Although long known, 1, 2‐and 1, 3‐dicarbonyl compounds have recently come
more and more to prevalence as ideal substrates for the invention of new stereoselective …