Bioengineered living bone grafts—A concise review on bioreactors and production techniques in vitro

P Kazimierczak, A Przekora - International journal of molecular sciences, 2022 - mdpi.com
It has been observed that bone fractures carry a risk of high mortality and morbidity. The
deployment of a proper bone healing method is essential to achieve the desired success …

The simpler, the better: tissue vascularization using the body's own resources

MW Laschke, MD Menger - Trends in Biotechnology, 2022 - cell.com
Tissue regeneration is crucially dependent on sufficient vascularization. In regenerative
medicine, this can be effectively achieved by autologous vascularization strategies using the …

[HTML][HTML] Harnessing the synergy of perfusable muscle flap matrix and adipose-derived stem cells for prevascularization and macrophage polarization to reconstruct …

Q Zhang, Y Chiu, Y Chen, Y Wu, LW Dunne, RD Largo… - Bioactive Materials, 2023 - Elsevier
Muscle flaps must have a strong vascular network to support a large tissue volume and
ensure successful engraftment. We developed porcine stomach musculofascial flap matrix …

Platelet-rich plasma as an alternative to xenogeneic sera in cell-based therapies: a need for standardization

E Anitua, M Zalduendo, M Troya, MH Alkhraisat… - International Journal of …, 2022 - mdpi.com
There has been an explosion in scientific interest in using human-platelet-rich plasma (PRP)
as a substitute of xenogeneic sera in cell-based therapies. However, there is a need to …

[HTML][HTML] A new semi-orthotopic bone defect model for cell and biomaterial testing in regenerative medicine

EA Sastre, Y Nossin, I Jansen, N Kops, C Intini… - Biomaterials, 2021 - Elsevier
In recent decades, an increasing number of tissue engineered bone grafts have been
developed. However, expensive and laborious screenings in vivo are necessary to assess …

Augmentation of Autologous Platelet-Rich Plasma in Hip Salvage in Stages I and II of Avascular Necrosis: Randomized Blinded Trial Comparing 3 Surgical …

N Palo, B Ray, M Lakhanpal, N Jeyaraman… - Indian Journal of …, 2024 - Springer
Introduction Avascular necrosis of the femoral head is common in routine orthopedic clinics.
The challenge arises in managing early stages (I and II) without obvious radiological …