[HTML][HTML] Materials engineering strategies for cancer vaccine adjuvant development

X Zhang, B Yang, Q Ni, X Chen - Chemical Society Reviews, 2023 - pubs.rsc.org
Cancer vaccines have emerged as a powerful new tool for cancer immunotherapy.
Adjuvants are vaccine ingredients that enhance the strength, velocity, and duration of the …

Engineering nanomaterial physical characteristics for cancer immunotherapy

DY Lee, K Huntoon, J Lux, BYS Kim… - Nature Reviews …, 2023 - nature.com
The physical properties of nanomaterials—such as size, structure, shape, charge,
mechanical strength and hydrophobicity—can directly or indirectly influence immune cell …

Self-Adjuvanting Polyguanidine Nanovaccines for Cancer Immunotherapy

X Zhang, K Wang, Z Zhao, X Shan, Y Wang, Z Feng… - ACS …, 2024 - ACS Publications
Tapping into the innate immune system's power, nanovaccines can induce tumor-specific
immune responses, which is a promising strategy in cancer immunotherapy. However …

[HTML][HTML] Spherical nucleic acids-based nanoplatforms for tumor precision medicine and immunotherapy

S Liu, CY Yu, H Wei - Materials Today Bio, 2023 - Elsevier
Precise diagnosis and treatment of tumors currently still face considerable challenges due to
the development of highly degreed heterogeneity in the dynamic evolution of tumors. With …

[HTML][HTML] Human serum albumin as the carrier to fabricate STING-activating peptide nanovaccine for antitumor immunotherapy

A Zheng, Z Ning, X Wang, Z Li, Y Sun, M Wu… - Materials Today Bio, 2024 - Elsevier
Tumor vaccines are emerging as one of the most promising therapeutic strategies for cancer
treatment. With the advantages of low toxicity, convenient production and stable quality …

Minimalist Nanovaccine with Optimized Amphiphilic Copolymers for Cancer Immunotherapy

L Niu, Y Miao, Z Cao, T Wei, J Zhu, M Li, B Bai… - ACS …, 2024 - ACS Publications
Cancer vaccines with the ability to elicit tumor-specific immune responses have attracted
significant interest in cancer immunotherapy. A key challenge for effective cancer vaccines is …

Polymer‐DNA Carriers Co‐Deliver Photosensitizer and siRNA for Light‐Promoted Gene Transfection and Hypoxia‐Relieved Photodynamic Therapy

G Fan, S Hou, W Zhang, H Jiang, F Xiao… - Angewandte Chemie …, 2024 - Wiley Online Library
Photochemical internalization is an efficient strategy relying on photodynamic reactions to
promote siRNA endosomal escape for the success of RNA‐interference gene regulation …

From Structure to Application: The Evolutionary Trajectory of Spherical Nucleic Acids

G Wang, S Han, Y Lu - Small, 2024 - Wiley Online Library
Since the proposal of the concept of spherical nucleic acids (SNAs) in 1996, numerous
studies have focused on this topic and have achieved great advances. As a new delivery …

Spherical nucleic acids: emerging amplifiers for therapeutic nanoplatforms

Z Tao, H Zhang, S Wu, J Zhang, Y Cheng, L Lei, Y Qin… - Nanoscale, 2024 - pubs.rsc.org
Gene therapy is a revolutionary treatment approach in the 21st century, offering significant
potential for disease prevention and treatment. However, the efficacy of gene delivery is …

Targeting the Skin: The Study of a Bottlebrush Polymer‐Antisense Oligonucleotide Conjugate in a Psoriasis Mouse Model

Y Fang, J Cai, F Fei, T Zhong, M Ren, D Wang, Y Li… - Small, 2024 - Wiley Online Library
The investigation of gene regulation therapeutics for the treatment of skin‐related diseases
is rarely explored in part due to inefficient systemic delivery. In this study, a bottlebrush …