Flaviviruses, such as dengue, Japanese encephalitis, tick-borne encephalitis, West Nile,
yellow fever, and Zika viruses, are critically important human pathogens that sicken a …

Dengue virus (DENV) is a mosquito-transmitted RNA virus responsible for 390 million
infections each year and significant morbidity and mortality throughout tropical and …

The formation of condensed matter typically involves a trade-off between structural order
and flexibility. As the extent and directionality of interactions between atomic or molecular …

Hepatitis B virus (HBV) is an enveloped DNA virus with a spherical capsid (or core). The
capsid is constructed from 120 copies of the homodimeric capsid protein arranged with T= 4 …

Zika virus (ZIKV) is an enveloped, mosquito-borne Flavivirus, which infects cells through
clathrin-mediated endocytosis and fusion employing acidic endosomes. Cell entry is mostly …

▪ Abstract Structural studies of polio-and closely related viruses have provided a series of
snapshots along their cell entry pathways. Based on the structures and related kinetic …

The activity of pleconaril in cell culture against prototypic enterovirus strains and 215 clinical
isolates of the most commonly isolated enterovirus serotypes was examined. The latter …

The monoclonal antibody 1A1D-2 has been shown to strongly neutralize dengue virus
serotypes 1, 2 and 3, primarily by inhibiting attachment to host cells. A crystal structure of its …

Most viruses use a hollow protein shell, the capsid, to enclose the viral genome. Virus
capsids are large, symmetric oligomers made of many copies of one or a few types of protein …

The picornavirus family consists of a large number of small RNA viruses, many of which are
significant pathogens of humans and livestock. They are amongst the simplest of vertebrate …