Traumatic brain injury and risk of neurodegenerative disorder

BL Brett, RC Gardner, J Godbout, K Dams-O'Connor… - Biological …, 2022 - Elsevier
Traumatic brain injury (TBI), particularly of greater severity (ie, moderate to severe), has
been identified as a risk factor for all-cause dementia and Parkinson's disease, with risk for …

Epidemiology of Parkinson's disease

A Elbaz, L Carcaillon, S Kab, F Moisan - Revue neurologique, 2016 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disease after
Alzheimer's. PD is considered a multifactorial disorder that results, in most cases, from the …

Epidemiology of mild traumatic brain injury and neurodegenerative disease

RC Gardner, K Yaffe - Molecular and Cellular Neuroscience, 2015 - Elsevier
Every year an estimated 42 million people worldwide suffer a mild traumatic brain injury
(MTBI) or concussion. More severe traumatic brain injury (TBI) is a well-established risk …

The spectrum of disease in chronic traumatic encephalopathy

AC McKee, TD Stein, CJ Nowinski, RA Stern… - Brain, 2013 - academic.oup.com
Chronic traumatic encephalopathy is a progressive tauopathy that occurs as a consequence
of repetitive mild traumatic brain injury. We analysed post-mortem brains obtained from a …

Mild TBI and risk of Parkinson disease: a chronic effects of neurotrauma consortium study

RC Gardner, AL Byers, DE Barnes, Y Li, J Boscardin… - Neurology, 2018 - AAN Enterprises
Objective Our aim was to assess risk of Parkinson disease (PD) following traumatic brain
injury (TBI), including specifically mild TBI (mTBI), among care recipients in the Veterans …

Long-term consequences of traumatic brain injury: current status of potential mechanisms of injury and neurological outcomes

HM Bramlett, WD Dietrich - Journal of neurotrauma, 2015 - liebertpub.com
Traumatic brain injury (TBI) is a significant clinical problem with few therapeutic interventions
successfully translated to the clinic. Increased importance on the progressive, long-term …

Association of traumatic brain injury with subsequent neurological and psychiatric disease: a meta-analysis

DC Perry, VE Sturm, MJ Peterson, CF Pieper… - Journal of …, 2016 - thejns.org
OBJECT Mild traumatic brain injury (TBI) has been proposed as a risk factor for the
development of Alzheimer's disease, Parkinson's disease, depression, and other illnesses …

Epidemiology and etiology of Parkinson's disease: a review of the evidence

K Wirdefeldt, HO Adami, P Cole, D Trichopoulos… - European journal of …, 2011 - Springer
The etiology of Parkinson's disease (PD) is not well understood but likely to involve both
genetic and environmental factors. Incidence and prevalence estimates vary to a large …

Traumatic brain injury: a disease process, not an event

BE Masel, DS DeWitt - Journal of neurotrauma, 2010 - liebertpub.com
Traumatic brain injury (TBI) is seen by the insurance industry and many health care
providers as an “event.” Once treated and provided with a brief period of rehabilitation, the …

Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic intervention

MG Tansey, MS Goldberg - Neurobiology of disease, 2010 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disease, after
Alzheimer's disease. The potential causes of PD remain uncertain, but recent studies …