Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies

BL Edlow, J Claassen, ND Schiff… - Nature Reviews Neurology, 2021 - nature.com
Substantial progress has been made over the past two decades in detecting, predicting and
promoting recovery of consciousness in patients with disorders of consciousness (DoC) …

The vegetative state/unresponsive wakefulness syndrome: a systematic review of prevalence studies

WS Van Erp, JCM Lavrijsen… - European journal of …, 2014 - Wiley Online Library
One of the worst outcomes of acquired brain injury is the vegetative state, recently renamed
'unresponsive wakefulness syndrome'(VS/UWS). A patient in VS/UWS shows reflexive …

Diagnostic precision of PET imaging and functional MRI in disorders of consciousness: a clinical validation study

J Stender, O Gosseries, MA Bruno, V Charland-Verville… - The Lancet, 2014 - thelancet.com
Background Bedside clinical examinations can have high rates of misdiagnosis of
unresponsive wakefulness syndrome (vegetative state) or minimally conscious state. The …

Therapies to restore consciousness in patients with severe brain injuries: a gap analysis and future directions

BL Edlow, LRD Sanz, L Polizzotto, N Pouratian… - Neurocritical care, 2021 - Springer
Abstract Background/Objective For patients with disorders of consciousness (DoC) and their
families, the search for new therapies has been a source of hope and frustration. Almost all …

What justifies the allocation of health care resources to patients with disorders of consciousness?

A Peterson, S Aas, D Wasserman - AJOB neuroscience, 2021 - Taylor & Francis
This paper critically engages ethical issues in the allocation of novel, and potentially costly,
health care resources to patients with disorders of consciousness. First, we review potential …

A heartbeat away from consciousness: heart rate variability entropy can discriminate disorders of consciousness and is correlated with resting-state fMRI brain …

F Riganello, SK Larroque, MA Bahri, L Heine… - Frontiers in …, 2018 - frontiersin.org
Background: Disorders of consciousness are challenging to diagnose, with inconsistent
behavioral responses, motor and cognitive disabilities, leading to approximately 40 …

Assessment of covert consciousness in the intensive care unit: clinical and ethical considerations

BL Edlow, JJ Fins - The Journal of head trauma rehabilitation, 2018 - journals.lww.com
Objective: To propose a practical ethical framework for how task-based functional magnetic
resonance imaging (fMRI) and electroencephalography (EEG) may be used in the intensive …

Assessment and management of pain/nociception in patients with disorders of consciousness or locked-in syndrome: A narrative review

EAC Bonin, N Lejeune, E Szymkowicz… - Frontiers in Systems …, 2023 - frontiersin.org
The assessment and management of pain and nociception is very challenging in patients
unable to communicate functionally such as patients with disorders of consciousness (DoC) …

[HTML][HTML] Towards modern post-coma care based on neuroscientific evidence

LRD Sanz, S Laureys, O Gosseries - International Journal of Clinical and …, 2023 - Elsevier
Background Understanding the mechanisms underlying human consciousness is pivotal to
improve the prognostication and treatment of severely brain-injured patients. Consciousness …

[图书][B] Biomechatronics

MB Popovic - 2024 - books.google.com
Biomechatronics is rapidly becoming one of the most influential and innovative research
directions defining the 21st century. The second edition Biomechatronics provides a …