[PDF][PDF] Oxidative stress and inflammatory markers in prediabetes and diabetes.

K Luc, A Schramm-Luc, TJ Guzik… - Journal of Physiology & …, 2019 - researchgate.net
Prediabetes is a state of elevated plasma glucose in which the threshold for diabetes has
not yet been reached and can predispose to the development of type 2 diabetes and …

Inflammation, metaflammation and immunometabolic disorders

GS Hotamisligil - Nature, 2017 - nature.com
Proper regulation and management of energy, substrate diversity and quantity, as well as
macromolecular synthesis and breakdown processes, are fundamental to cellular and …

Carotid intima-media thickness progression as surrogate marker for cardiovascular risk: meta-analysis of 119 clinical trials involving 100 667 patients

P Willeit, L Tschiderer, E Allara, K Reuber… - Circulation, 2020 - Am Heart Assoc
Background: To quantify the association between effects of interventions on carotid intima-
media thickness (cIMT) progression and their effects on cardiovascular disease (CVD) risk …

Foundations of immunometabolism and implications for metabolic health and disease

GS Hotamisligil - Immunity, 2017 - cell.com
Highly ordered interactions between immune and metabolic responses are evolutionarily
conserved and paramount for tissue and organismal health. Disruption of these interactions …

Effects of SGLT2 inhibitors on systemic and tissue low-grade inflammation: the potential contribution to diabetes complications and cardiovascular disease

F Bonnet, AJ Scheen - Diabetes & metabolism, 2018 - Elsevier
Chronic low-grade inflammation is a recognized key feature associated with type 2 diabetes
mellitus (T2DM) and its complications. In prospective randomized trials, sodium-glucose …

Anti‐inflammatory Effects of Empagliflozin and Gemigliptin on LPS‐Stimulated Macrophage via the IKK/NF‐κB, MKK7/JNK, and JAK2/STAT1 Signalling Pathways

N Lee, YJ Heo, SE Choi, JY Jeon… - Journal of …, 2021 - Wiley Online Library
Background. Sodium‐glucose cotransporter 2 (SGLT2) and dipeptidyl peptidase‐4 (DPP‐4)
inhibitors are glucose‐lowering drugs whose anti‐inflammatory properties have recently …

[HTML][HTML] Steatotic liver disease, MASLD and risk of chronic kidney disease

J Bilson, A Mantovani, CD Byrne, G Targher - Diabetes & metabolism, 2024 - Elsevier
With the rising tide of fatty liver disease related to metabolic dysfunction worldwide, the
association of this common liver disease with chronic kidney disease (CKD) has become …

[HTML][HTML] Type 2 diabetes mellitus and osteoarthritis

N Veronese, C Cooper, JY Reginster… - Seminars in arthritis and …, 2019 - Elsevier
Objectives Type 2 diabetes mellitus (T2DM) and osteoarthritis (OA) are common diseases
that frequently co-exist, along with overweight/obesity. While the mechanical impact of …

Exercise and type 2 diabetes: focus on metabolism and inflammation

K Karstoft, BK Pedersen - Immunology and cell biology, 2016 - Wiley Online Library
Type 2 diabetes mellitus (T2DM) is associated with metabolic dysregulation and chronic
inflammation, and regular exercise may provide a strong stimulus for improving both. In this …

Autophagy-nutrient sensing pathways in diabetic complications

UM Parmar, MP Jalgaonkar, YA Kulkarni… - Pharmacological …, 2022 - Elsevier
The incidence of diabetes has been increasing in recent decades which is affecting the
population of both, developed and developing countries. Diabetes is associated with micro …