Cognitive decline is increasingly described as a co‐morbidity of temporal lobe epilepsy
(TLE). Mechanisms underlying cognitive impairment are not fully understood despite …

Epilepsy is the fourth most common neurological disorder, but current treatment options
provide limited efficacy and carry the potential for problematic adverse effects. There is an …

Progressive functional decline in the epilepsies is largely unexplained. We formed the
ENIGMA-Epilepsy consortium to understand factors that influence brain measures in …

В руководстве представлены результаты 60-летней работы автора в области детской
и взрослой неврологии и эпилептологии. Впервые эпилептология представлена в …

Importance It is controversial whether epilepsy is a static or progressive disease. Evidence
of progressive gray matter loss in epilepsy would support early diagnosis, rapid treatment …

Objective We used whole brain T1-weighted MRI to estimate the age of individuals with
medically refractory focal epilepsy, and compared with individuals with newly diagnosed …

Mesial temporal lobe epilepsy (mTLE) is a neurological disorder in which patients suffer
from frequent consciousness‐impairing seizures, broad neurocognitive deficits, and …

A recent article by Farrell et al. characterizes the phenomenon, mechanisms, and treatment
of a local and severe hypoperfusion/hypoxia event that occurs in brain regions following a …

Focal epilepsy in adults is associated with progressive atrophy of the cortex at a rate more
than double that of normal ageing. We aimed to determine whether successful epilepsy …

Objective Epilepsies are a group of neurological disorders sharing certain core features, but
also demonstrate remarkable pathogenic and symptomatic heterogeneities. Various …