Computational analysis of cardiac contractile function
Abstract Purpose of Review Heart failure results in the high incidence and mortality all over
the world. Mechanical properties of myocardium are critical determinants of cardiac function …
the world. Mechanical properties of myocardium are critical determinants of cardiac function …
Integrating 4-D light-sheet fluorescence microscopy and genetic zebrafish system to investigate ambient pollutants-mediated toxicity
Ambient air pollutants, including PM 2.5 (aerodynamic diameter d~ 2.5 μm), PM 10 (d~ 10
μm), and ultrafine particles (UFP: d< 0.1 μm) impart both short-and long-term toxicity to …
μm), and ultrafine particles (UFP: d< 0.1 μm) impart both short-and long-term toxicity to …
[HTML][HTML] 4D Light-sheet imaging and interactive analysis of cardiac contractility in zebrafish larvae
Despite ongoing efforts in cardiovascular research, the acquisition of high-resolution and
high-speed images for the purpose of assessing cardiac contraction remains challenging …
high-speed images for the purpose of assessing cardiac contraction remains challenging …
A hybrid of light-field and light-sheet imaging to study myocardial function and intracardiac blood flow during zebrafish development
Biomechanical forces intimately contribute to cardiac morphogenesis. However, volumetric
imaging to investigate the cardiac mechanics with high temporal and spatial resolution …
imaging to investigate the cardiac mechanics with high temporal and spatial resolution …
Dihydroartemisinin alleviates doxorubicin‐induced cardiotoxicity and ferroptosis by activating Nrf2 and regulating autophagy
ZH Lin, HQ Xiang, YW Yu, YJ Xue, C Wu… - The FASEB …, 2024 - Wiley Online Library
Although the use of Doxorubicin (Dox) is extensive in the treatment of malignant tumor, the
toxic effects of Dox on the heart can cause myocardial injury. Therefore, it is necessary to …
toxic effects of Dox on the heart can cause myocardial injury. Therefore, it is necessary to …
Saak transform-based machine learning for light-sheet imaging of cardiac trabeculation
Objective: Recent advances in light-sheet fluorescence microscopy (LSFM) enable 3-
dimensional (3-D) imaging of cardiac architecture and mechanics in toto. However …
dimensional (3-D) imaging of cardiac architecture and mechanics in toto. However …
Effect of captopril on post-infarction remodelling visualized by light sheet microscopy and echocardiography
U Roostalu, L Thisted, JL Skytte, CG Salinas… - Scientific reports, 2021 - nature.com
Angiotensin converting enzyme inhibitors, among them captopril, improve survival following
myocardial infarction (MI). The mechanisms of captopril action remain inadequately …
myocardial infarction (MI). The mechanisms of captopril action remain inadequately …
[HTML][HTML] Integrative transcriptomics and cell systems analyses reveal protective pathways controlled by Igfbp-3 in anthracycline-induced cardiotoxicity
Anthracyclines such as doxorubicin (Dox) are effective chemotherapeutic agents, however
their use is hampered by subsequent cardiotoxicity risk. Our understanding of cardiomyocyte …
their use is hampered by subsequent cardiotoxicity risk. Our understanding of cardiomyocyte …
Quantitative 4D imaging of biomechanical regulation of ventricular growth and maturation
Abnormal cardiac development is intimately associated with congenital heart disease.
During development, a sponge-like network of muscle fibers in the endocardium, known as …
During development, a sponge-like network of muscle fibers in the endocardium, known as …
Novel mechanisms, imaging approaches, and management strategies for anthracycline-induced cardiotoxicity
RRS Packard, EH Yang - Frontiers in Cardiovascular Medicine, 2023 - frontiersin.org
Anthracyclines remain one of the essential chemotherapy class drugs due to their effective
antineoplastic properties in multiple adult and pediatric cancers. Decades of observed …
antineoplastic properties in multiple adult and pediatric cancers. Decades of observed …