This mini-review summarizes the current evidence for the role of macrophage activation and
polarization in inflammation and immune response pertinent to interstitial lung disease …

Simple Summary Lung cancer is the leading cause of mortality in cancer patients, causing
an estimated 1.8 million deaths in the year 2020. However, the available therapeutic options …

Macrophages are immune cells that play different roles under different physiological
conditions. They are present in all tissues where they primarily protect from bacteria and …

The characteristics of monocyte/macrophage lineage are diversity and plasticity, mainly
manifested by M1 and M2 subtypes in the body tissues, and playing different roles in the …

Background Previous investigations of transcriptomic signatures of cancer patient survival
and post-therapy relapse have focused on tumor tissue. In contrast, here we show that in …

Precise expression and regulation of genes in the immune system is important for organisms
to produce strong immunity towards pathogens and limit autoimmunity. In recent years, an …

Introduction Local and regional recurrence after surgical intervention is a significant problem
in cancer management. The multistage theory of carcinogenesis precisely places the …

Background: Non-small cell lung cancer (NSCLC) is still one of the types of cancer with the
highest death rates. MicroRNAs (miRNAs) play essential roles in NSCLC development. This …

Exosome is an important way for tumor cells to communicate with other cells and plays an
important role in tumor progression. Previous studies revealed that miR-195-5p acts as a …

Nonalcoholic fatty liver disease (NAFLD) is the most prevalent liver pathology worldwide.
Meanwhile, liver cancer represents the sixth most common malignancy, with hepatocellular …