[HTML][HTML] TGR5 signalling in heart and brain injuries: focus on metabolic and ischaemic mechanisms

N Xu, Y He, C Zhang, Y Zhang, S Cheng, L Deng… - Neurobiology of …, 2024 - Elsevier
The heart and brain are the core organs of the circulation and central nervous system,
respectively, and play an important role in maintaining normal physiological functions. Early …

Epigenetically altered macrophages promote development of diabetes-associated atherosclerosis

D Huang, W Gao, X Zhong, H Wu, Y Zhou… - Frontiers in …, 2023 - frontiersin.org
Background Atherosclerosis (AS) risk is elevated in diabetic patients, but the underlying
mechanism such as involvement of epigenetic control of foam macrophages remains …

[PDF][PDF] Carvone's hypoglycemic and hypolipidemic potent activity via regulation insulin-induced genes in diabetic hyperlipidemic rats

N Zein, M Shehata, AM Amer - … Research in Applied …, 2023 - biointerfaceresearch.com
Carvone is a monoterpene and component of many essential oils from medicinal plants. Our
research intended to evaluate the therapeutic efficacy of carvone in the handling of diabetes …

[HTML][HTML] Characterization of Potentially Inappropriate Medications That Need Special Attention in the Elderly with Dementia by Analyzing Pharmacy Claims Data

Y Kasanami, T Yamamoto, T Miyamoto… - Biological and …, 2023 - jstage.jst.go.jp
Community pharmacists may play a key role in promoting deprescribing of potential
inappropriate medications (PIMs) that are highly prevalent among community-dwelling …

A cross-country analysis of episodic memory and (potentially) modifiable risk factors of dementia

D Knapp, A Kapteyn, A Giambrone, T Ozawa - medRxiv, 2024 - medrxiv.org
Abstract The widely cited Lancet Commission concluded that 40% of dementia cases may
be preventable through interventions targeting what they refer to as modifiable risk factors …

Effect Of High Fat Diet Induced Metabolic Syndrome And Treatment With Insulin Like Growth Factor 1 On Biochemical And Immunohistochemical Parameters Related …

AF Yousuf, SZ Elshora, MG Abdallah… - Egyptian Journal of …, 2023 - ejchem.journals.ekb.eg
The prevalence of metabolic syndrome (MetS) makes type 2 diabetes mellitus and its
consequences more common in communities. Dysfunctions of the nervous system has …

[PDF][PDF] Influence of Pro-and Anti-inflammatory Cytokines during Pathogenesis Atherosclerosis: A Dynamical Approach

A Adak, A Devi, PK Gupta - 2022 - scholar.archive.org
The role of anti-cytokines in atherosclerosis is to reduce the inflammation in the intima. In
some situations, certain anti-inflammatory cytokines like TGF-beta and IL-6 have shown the …

[引用][C] Aus dem Zentrum für Kardiologie der Universitätsmedizin der Johannes Gutenberg-Universität Mainz

A Al Zuabi - openscience.ub.uni-mainz.de
PKA Proteinkinase A PKC Proteinkinase C PLC Phospholipase C qRT-PCR quantitative
real time polymerase chain reaction RAAS Renin-Angiotensin-Aldosteron-System RNA …

[PDF][PDF] Cav3. 2 T 型Ca2+ チャネルを標的とする新規鎮痛薬の開発と保険薬局レセプトデータ解析による高齢認知症患者に特徴的な潜在的不適切処方の同定に関する研究

笠波嘉人, カサナミヨシヒト - 博士学位論文/内容の要旨および審査 …, 2023 - kindai.repo.nii.ac.jp
日本における慢性疼痛の保有率は 15.4~ 39.3% に上ると言われる. 慢性疼痛は,
痛みが強い場合には患者の QOL を著しく低下させる他, 就労困難などを伴う場合は社会的損失も …