The ability to form biofilms is a crucial virulence trait for several microorganisms, including
Klebsiella pneumoniae–a Gram-negative encapsulated bacterium often associated with …

Biofilm refers to the complex, sessile communities of microbes found either attached to a
surface or buried firmly in an extracellular matrix as aggregates. The biofilm matrix …

Klebsiella oxytoca is actually a complex of nine species—Klebsiella grimontii, Klebsiella
huaxiensis, Klebsiella michiganensis, K. oxytoca, Klebsiella pasteurii, Klebsiella …

Biofilms are communities of microorganisms that are attached to a surface and play a
significant role in the persistence of bacterial infections. Bacteria within a biofilm are several …

A new hypervirulent (hypermucoviscous) variant of Klebsiella pneumoniae has emerged.
First described in the Asian Pacific Rim, it now increasingly recognized in Western countries …

Twenty-five years have passed since the discovery of cyclic dimeric (3′→ 5′) GMP (cyclic
di-GMP or c-di-GMP). From the relative obscurity of an allosteric activator of a bacterial …

Recent research has revealed that horizontal gene transfer and biofilm formation are
connected processes. Although published research investigating this interconnectedness is …

Awareness of the role of Klebsiella pneumoniae as an important opportunistic pathogen of
the urinary tract in compromised individuals and hospitalized patients has increased over …

For an organism to survive, it must be able to sense its environment and regulate
physiological processes accordingly. Understanding how bacteria integrate signals from …

Cyclic di-GMP (c-di-GMP) synthetases and hydrolases (GGDEF, EAL, and HD-GYP
domains) can be readily identified in bacterial genome sequences by using standard …