[HTML][HTML] Curcumin: An epigenetic regulator and its application in cancer

T Ming, Q Tao, S Tang, H Zhao, H Yang, M Liu… - Biomedicine & …, 2022 - Elsevier
Nowadays, one of the leading causes of death in humans is cancer, which is still on the rise
globally and is in great need of intense study on the pathogenic mechanism and effective …

Therapeutic potential and pharmaceutical development of a multitargeted flavonoid phloretin

KT Nakhate, H Badwaik, R Choudhary, K Sakure… - Nutrients, 2022 - mdpi.com
Phloretin is a flavonoid of the dihydrogen chalcone class, present abundantly in apples and
strawberries. The beneficial effects of phloretin are mainly associated with its potent …

Berberine is a suppressor of Hedgehog signaling cascade in colorectal cancer

Q Sun, Q Tao, T Ming, S Tang, H Zhao, M Liu, H Yang… - Phytomedicine, 2023 - Elsevier
Background Colorectal cancer (CRC) is a malignant affliction that burdens people globally.
Overactivated Hedgehog signal is highly implicated in CRC pathogenesis. Phytochemical …

Spectroscopy and molecular simulation on the interaction of Nano-Kaempferol prepared by oil-in-water with two carrier proteins: An investigation of protein–protein …

M Kaffash, S Tolou-Shikhzadeh-Yazdi… - … Acta Part A: Molecular …, 2024 - Elsevier
In this work, the interaction of human serum albumin (HSA) and human holo-transferrin
(HTF) with the prepared Nano-Kaempferol (Nano-KMP) through oil-in-water procedure was …

New perspective of the ternary complex of nano-curcumin with β-lactoglobulin in the presence of α-lactalbumin: Spectroscopic and molecular dynamic investigations

M Tabasi, P Maghami, Z Amiri-Tehranizadeh… - Journal of Molecular …, 2023 - Elsevier
Understanding the interaction between nano-curcumin (Nano Cur) and proteins is essential
for elucidating the potential therapeutic applications of curcumin in nano formulations. In this …

Interaction of two commercial azobenzene food dyes, amaranth and new coccine, with human serum albumin: Biophysical characterization

OA Chaves, RJS Loureiro, A Costa-Tuna… - ACS Food Science & …, 2023 - ACS Publications
Food processing and storage cause natural food color to diminish, leading to the addition of
synthetic dyes by the industry. Unfortunately, these dyes have potential health risks, such as …

Multi-spectroscopic investigation, molecular docking and molecular dynamic simulation of competitive interactions between flavonoids (quercetin and rutin) and …

NA Alsaif, TA Wani, AH Bakheit, S Zargar - International Journal of …, 2020 - Elsevier
The main mechanism for drug-drug interaction is displacement reaction of ligands from their
protein binding sites. The aim of this study was to evaluate anticancer drug sorafenib …

Green synthesis of NiO nanoparticles using Aloe vera gel extract and evaluation of antimicrobial activity

B Ahmad, MI Khan, MA Naeem, A Alhodaib… - Materials Chemistry and …, 2022 - Elsevier
A cost effective and eco-benign green synthesis was adopted for the synthesis of nickel
oxide (NiO) nanoparticles (NPs) using Aloe vera gel and effect of temperature (300, 400 and …

A review on prevention of glycation of proteins: Potential therapeutic substances to mitigate the severity of diabetes complications

S Sarmah, AS Roy - International Journal of Biological Macromolecules, 2022 - Elsevier
Non-enzymatic reaction involving carbonyl of reducing sugars and amino groups in proteins
produces advanced glycation end products (AGEs). AGE accumulation in vivo is a crucial …

Binding and drug displacement study of colchicine and bovine serum albumin in presence of azithromycin using multispectroscopic techniques and molecular …

TA Wani, AH Bakheit, AA Al-Majed, N Altwaijry… - Journal of Molecular …, 2021 - Elsevier
The binding and displacement interaction of colchicine and azithromycin to the model
transport protein bovine serum albumin (BSA) was evaluated in this study. Azithromycin, a …