Bruch's membrane: a key consideration with complement-based therapies for age-related macular degeneration
The complement system is crucial for immune surveillance, providing the body's first line of
defence against pathogens. However, an imbalance in its regulators can lead to …
defence against pathogens. However, an imbalance in its regulators can lead to …
Gene therapy to the retina and the cochlea
R Crane, SM Conley, MR Al-Ubaidi… - Frontiers in …, 2021 - frontiersin.org
Vision and hearing disorders comprise the most common sensory disorders found in people.
Many forms of vision and hearing loss are inherited and current treatments only provide …
Many forms of vision and hearing loss are inherited and current treatments only provide …
The landscape of non-viral gene augmentation strategies for inherited retinal diseases
L Toualbi, M Toms, M Moosajee - International Journal of Molecular …, 2021 - mdpi.com
Inherited retinal diseases (IRDs) are a heterogeneous group of disorders causing
progressive loss of vision, affecting approximately one in 1000 people worldwide. Gene …
progressive loss of vision, affecting approximately one in 1000 people worldwide. Gene …
[HTML][HTML] Successful transduction of target gene mediated by adeno-associated virus 2 into lens epithelial cells in rats
Y Liang, T Lan, Q Gan, H Liang - Journal of Virological Methods, 2023 - Elsevier
Abstract The Adeno-Associated Virus (AAV) has emerged as a promising candidate for
delivery of genetic material, exhibiting significant potential in various clinical applications …
delivery of genetic material, exhibiting significant potential in various clinical applications …