The pathogenesis of rheumatoid arthritis

S Alivernini, GS Firestein, IB McInnes - Immunity, 2022 - cell.com
Significant recent progress in understanding rheumatoid arthritis (RA) pathogenesis has led
to improved treatment and quality of life. The introduction of targeted-biologic and-synthetic …

Immunopathogenesis of rheumatoid arthritis

GS Firestein, IB McInnes - Immunity, 2017 - cell.com
Rheumatoid arthritis (RA) is the most common inflammatory arthropathy. The majority of
evidence, derived from genetics, tissue analyses, models, and clinical studies, points to an …

The pre-clinical phase of rheumatoid arthritis: from risk factors to prevention of arthritis

N Petrovská, K Prajzlerová, J Vencovský, L Šenolt… - Autoimmunity …, 2021 - Elsevier
Rheumatoid arthritis (RA) is a chronic autoimmune disease considered as a multistep
process spanning from the interaction of genetic (eg, shared epitope or non-HLA loci) …

Understanding the dynamics: pathways involved in the pathogenesis of rheumatoid arthritis

E Choy - Rheumatology, 2012 - academic.oup.com
RA is a progressive inflammatory autoimmune disease with articular and systemic effects. Its
exact cause is unknown, but genetic and environmental factors are contributory. T cells, B …

Evolving concepts of rheumatoid arthritis

GS Firestein - Nature, 2003 - nature.com
Rheumatoid arthritis is the most common inflammatory arthritis and is a major cause of
disability. It existed in early Native American populations several thousand years ago but …

Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins

AJ MacGregor, H Snieder, AS Rigby… - … : Official Journal of …, 2000 - Wiley Online Library
Objective Twin concordance data for rheumatoid arthritis (RA) on their own provide only
limited insight into the relative genetic and environmental contribution to the disease. We …

Epidemiology of adult rheumatoid arthritis

Y Alamanos, AA Drosos - Autoimmunity reviews, 2005 - Elsevier
Several incidence and prevalence studies of rheumatoid arthritis (RA) have been reported
during the last decades, suggesting a considerable variation of the disease occurrence …

The epidemiology of rheumatoid arthritis

SE Gabriel - Rheumatic disease clinics of north America, 2001 - Elsevier
Epidemiology is the study of the distribution and determinants of disease in human
populations. 21 This definition is based on two fundamental assumptions: first, that human …

[图书][B] Handbook of nutraceuticals and functional foods

REC Wildman, R Wildman, TC Wallace - 2016 - taylorfrancis.com
Scientific advances in this field have not only given us a better understanding of what is an
optimal diet, but has allowed food and nutraceutical companies to market products with …

Цитокины в патогенезе и лечении заболеваний человека

АС Симбирцев - 2018 - elibrary.ru
В монографии приведены сведения по роли цитокинов в регуляции физиологических
процессов, защитных реакций организма и в патогенезе иммунопатологических …