Neural dedifferentiation in the aging brain

JD Koen, MD Rugg - Trends in cognitive sciences, 2019 - cell.com
Many cognitive abilities decline with age even in the absence of detectable pathology.
Recent evidence indicates that age-related neural dedifferentiation, operationalized in terms …

Inhibitory neurotransmission, plasticity and aging in the mammalian central auditory system

DM Caspary, L Ling, JG Turner… - Journal of …, 2008 - journals.biologists.com
Aging and acoustic trauma may result in partial peripheral deafferentation in the central
auditory pathway of the mammalian brain. In accord with homeostatic plasticity, loss of …

Age differences in neural distinctiveness revealed by multi-voxel pattern analysis

J Carp, J Park, TA Polk, DC Park - Neuroimage, 2011 - Elsevier
Current theories of cognitive aging argue that neural representations become less distinctive
in old age, a phenomenon known as dedifferentiation. The present study used multi-voxel …

[HTML][HTML] The effects of aging on motion detection and direction identification

PJ Bennett, R Sekuler, AB Sekuler - Vision research, 2007 - Elsevier
Random dot cinematograms were used to probe motion perception in human observers
ranging from 23 to 81years of age. Stimuli were either broadband directional Noise, which …

Aging and vision: changes in function and performance from optics to perception

GJ Andersen - Wiley Interdisciplinary Reviews: Cognitive …, 2012 - Wiley Online Library
Age‐related declines in vision can have a major impact on the health and well‐being of an
older population. A review of research on aging and vision indicates that these declines …

Perceptual learning improves contrast sensitivity of V1 neurons in cats

T Hua, P Bao, CB Huang, Z Wang, J Xu, Y Zhou, ZL Lu - Current biology, 2010 - cell.com
Background Perceptual learning has been documented in adult humans over a wide range
of tasks. Although the often-observed specificity of learning is generally interpreted as …

Reduced neural selectivity increases fMRI adaptation with age during face discrimination

JO Goh, A Suzuki, DC Park - Neuroimage, 2010 - Elsevier
Ventral–visual activity in older adults has been characterized by dedifferentiation, or
reduced distinctiveness, of responses to different categories of visual stimuli such as faces …

[HTML][HTML] Differential aging of motion processing mechanisms: Evidence against general perceptual decline

J Billino, F Bremmer, KR Gegenfurtner - Vision research, 2008 - Elsevier
While the percentage of older people in our society is steadily increasing, knowledge about
perceptual changes during healthy aging is still limited. We investigated age effects on …

Multisensory integration, aging, and the sound-induced flash illusion.

DJ DeLoss, RS Pierce, GJ Andersen - Psychology and aging, 2013 - psycnet.apa.org
The present study examined age-related differences in multisensory integration and the role
of attention in age-related differences in multisensory integration. The sound-induced flash …

Critical periods of brain development

JM Cisneros-Franco, P Voss, ME Thomas… - Handbook of clinical …, 2020 - Elsevier
Brain plasticity is maximal at specific time windows during early development known as
critical periods (CPs), during which sensory experience is necessary to establish optimal …