Social cognition in schizophrenia

MF Green, WP Horan, J Lee - Nature Reviews Neuroscience, 2015 - nature.com
Individuals with schizophrenia exhibit impaired social cognition, which manifests as
difficulties in identifying emotions, feeing connected to others, inferring people's thoughts …

[HTML][HTML] Self-soothing behaviors with particular reference to oxytocin release induced by non-noxious sensory stimulation

K Uvnäs-Moberg, L Handlin - Frontiers in psychology, 2015 - frontiersin.org
Oxytocin, a hypothalamic nonapeptide, is linked to increased levels of social interaction, well-
being and anti-stress effects. The effects of oxytocin that is released by sensory stimulation …

Pharmacological treatment of schizophrenia: a critical review of the pharmacology and clinical effects of current and future therapeutic agents

S Miyamoto, N Miyake, LF Jarskog… - Molecular …, 2012 - nature.com
Since the introduction of chlorpromazine and throughout the development of the new-
generation antipsychotic drugs (APDs) beginning with clozapine, the D 2 receptor has been …

[HTML][HTML] Negative symptoms of schizophrenia: clinical characteristics, pathophysiological substrates, experimental models and prospects for improved treatment

MJ Millan, K Fone, T Steckler, WP Horan - European …, 2014 - Elsevier
Schizophrenia is a complex and multifactorial disorder generally diagnosed in young adults
at the time of the first psychotic episode of delusions and hallucinations. These positive …

Sniffing around oxytocin: review and meta-analyses of trials in healthy and clinical groups with implications for pharmacotherapy

MJ Bakermans-Kranenburg… - Translational …, 2013 - nature.com
The popularity of oxytocin (OT) has grown exponentially during the past decade, and so has
the number of OT trials in healthy and clinical groups. We take stock of the evidence from …

Towards a neuroscience of empathy: ontogeny, phylogeny, brain mechanisms, context and psychopathology

C Gonzalez-Liencres, SG Shamay-Tsoory… - … & Biobehavioral Reviews, 2013 - Elsevier
Empathy allows individuals to share the affective states of others, predict others' actions, and
stimulate prosocial behavior. Whilst the proximate mechanisms of empathy, modulated in …

A critical review of the influence of oxytocin nasal spray on social cognition in humans: evidence and future directions

AJ Graustella, C MacLeod - Hormones and behavior, 2012 - Elsevier
The past eight years of research has demonstrated that oxytocin nasal spray has a
significant impact on human social cognition. The aim of this review is to provide critical …

Immunohistochemical localization of oxytocin receptors in human brain

ML Boccia, P Petrusz, K Suzuki, L Marson… - Neuroscience, 2013 - Elsevier
The neuropeptide oxytocin (OT) regulates rodent, primate and human social behaviors and
stress responses. OT binding studies employing 125 Id (CH 2) 5-[Tyr (Me) 2, Thr 4, Tyr-NH 2 …

The role of oxytocin in psychiatric disorders: a review of biological and therapeutic research findings

DM Cochran, D Fallon, M Hill… - Harvard review of …, 2013 - journals.lww.com
Identify the biological role of oxytocin in forming attachments. Evaluate the relationship
between various neuropsychiatric disorders and oxytocin. Identify clinical implications of …

Intranasal treatment of central nervous system dysfunction in humans

CD Chapman, WH Frey, S Craft, L Danielyan… - Pharmaceutical …, 2013 - Springer
One of the most challenging problems facing modern medicine is how to deliver a given
drug to a specific target at the exclusion of other regions. For example, a variety of …