[HTML][HTML] Regulation of MCL1 through a serum response factor/Elk-1-mediated mechanism links expression of a viability-promoting member of the BCL2 family to the …
KJ Townsend, P Zhou, L Qian, CK Bieszczad… - Journal of Biological …, 1999 - ASBMB
Proliferation, differentiation, and apoptosis are tightly regulated during hematopoiesis,
allowing amplification along specific lineages while preventing excessive proliferation of …
allowing amplification along specific lineages while preventing excessive proliferation of …
Retinoic acid causes MEK-dependent RAF phosphorylation through RARα plus RXR activation in HL-60 cells
HY Hong, S Varvayanis, A Yen - Differentiation, 2001 - Elsevier
Retinoic acid (RA) is known to cause the myeloid differentiation of HL-60 human
myeloblastic leukemia cells in a process requiring MEK-dependent ERK2 activation. This …
myeloblastic leukemia cells in a process requiring MEK-dependent ERK2 activation. This …
Antiproliferative Effect of 13-cis-Retinoic Acid is Associated with Granulocyte Differentiation and Decrease in Cyclin B1 and Bcl-2 Protein Levels in G0/G1 Arrested HL …
A Vuletic, G Konjevic, D Milanovic, S Ruzdijic… - Pathology & Oncology …, 2010 - Springer
Retinoic acid (RA), similar to specific growth factors, can induce differentiation of
proliferating promyelocytic precursors into terminally differentiated granulocytes, although …
proliferating promyelocytic precursors into terminally differentiated granulocytes, although …
Retinoic acid induces nuclear accumulation of Raf1 during differentiation of HL-60 cells
J Smith, RP Bunaciu, G Reiterer, D Coder… - Experimental cell …, 2009 - Elsevier
All trans-retinoic acid (RA) is a standard therapeutic agent used in differentiation induction
therapy treatment of acute promyelocytic leukemia (APL). RA and its metabolites use a …
therapy treatment of acute promyelocytic leukemia (APL). RA and its metabolites use a …
Combination of retinoic acid and tumor necrosis factor overcomes the maturation block in a variety of retinoic acid-resistant acute promyelocytic leukemia cells
M Witcher, HY Shiu, Q Guo, WH Miller Jr - Blood, 2004 - ashpublications.org
Retinoic acid (RA) overcomes the maturation block in t (15: 17) acute promyelocytic
leukemia (APL), leading to granulocytic differentiation. Patients receiving RA alone …
leukemia (APL), leading to granulocytic differentiation. Patients receiving RA alone …
Human myeloblastic leukemia cells (HL-60) express a membrane receptor for estrogen that signals and modulates retinoic acid-induced cell differentiation
MA Kauss, G Reiterer, RP Bunaciu, A Yen - Experimental cell research, 2008 - Elsevier
Estrogen receptors are historically perceived as nuclear ligand activated transcription
factors. An estrogen receptor has now been found localized to the plasma membrane of …
factors. An estrogen receptor has now been found localized to the plasma membrane of …
Retinoic acid-induced blr1 expression promotes ERK2 activation and cell differentiation in HL-60 cells
TE Battle, RA Levine, A Yen - Experimental cell research, 2000 - Elsevier
Retinoids are known to induce the differentiation and cell cycle arrest of human myeloid
leukemia cells in vitro. Differential display was used to identify putative early regulatory …
leukemia cells in vitro. Differential display was used to identify putative early regulatory …
Retinoic acid increases amount of phosphorylated RAF; ectopic expression of cFMS reveals that retinoic acid-induced differentiation is more strongly dependent on …
A Yen, R Sturgill, S Varvayanis - In Vitro Cellular & Developmental Biology …, 2000 - Springer
Retinoic acid is known to cause the myeloid differentiation and G1/0 cell cycle arrest of HL-
60 cells in a process that requires mitogen-activated protein/extracellular signal regulated …
60 cells in a process that requires mitogen-activated protein/extracellular signal regulated …
Retinoic acid induces expression of SLP-76: expression with c-FMS enhances ERK activation and retinoic acid-induced differentiation/G0 arrest of HL-60 cells
A Yen, S Varvayanis, JL Smith, TJ Lamkin - European journal of cell biology, 2006 - Elsevier
Retinoic acid (RA) is known to cause MAPK signaling which propels G0 arrest and myeloid
differentiation of HL-60 human myeloblastic leukemia cells. The present studies show that …
differentiation of HL-60 human myeloblastic leukemia cells. The present studies show that …
Phosphorylation of retinoblastoma protein assayed in individual HL-60 cells during their proliferation and differentiation
G Juan, X Li, Z Darzynkiewicz - Experimental cell research, 1998 - Elsevier
Expression of pRb and its state of phosphorylation were immunocytochemically assayed in
individual HL-60 cells during their proliferation and after induction of differentiation, using …
individual HL-60 cells during their proliferation and after induction of differentiation, using …