RNA-based therapies have catalyzed a revolutionary transformation in the biomedical
landscape, offering unprecedented potential in disease prevention and treatment. However …

Chemodynamic therapy (CDT) is well-known for using the tumor microenvironment to
activate the Fenton reaction or Fenton-like reaction to generate strong oxidative hydroxyl …

Alzheimer's disease (AD) is caused by a complex interaction between genetic and
environmental factors. However, how the role of peripheral organ changes in response to …

Lipid nanoparticles (LNPs) have emerged as leading non-viral carriers for messenger RNA
(mRNA) delivery in clinical applications. Overcoming challenges in safe and effective mRNA …

Liver disease is increasing in incidence and is the third most common cause of premature
death in the United Kingdom and fourth in the United States. Liver disease accounts for 2 …

Liver diseases have consistently posed substantial challenges to global health. It is crucial
to find innovative methods to effectively prevent and treat these diseases. In recent times …

Lipid nanoparticles (LNPs) have proven themselves as transformative actors in chimeric
antigen receptor (CAR) T cell therapy, surpassing traditional methods and addressing …

Nucleic acid therapeutics have demonstrated substantial potential in combating various
diseases. However, challenges persist, particularly in the delivery of multifunctional nucleic …

One of the critical steps in gene therapy is the successful delivery of the genes.
Immunogenicity and toxicity are major issues for viral gene delivery systems. Thus, non-viral …

Fungal keratitis (FK) is a serious, potentially sight-threatening corneal infection, which is
associated with poor prognosis. A20, also called TNFAIP3, plays significant roles in the …