Large-vessel vasculitis (LVV) manifests as inflammation of the aorta and its major branches
and is the most common primary vasculitis in adults. LVV comprises two distinct conditions …

In the last few decades, our understanding of Langerhans cells (LCs) has drastically
changed based on novel findings regarding the developmental origin and biological …

Background: Giant cell arteritis, a chronic autoimmune disease of the aorta and its large
branches, is complicated by aneurysm formation, dissection, and arterial occlusions. Arterial …

Giant cell arteritis (GCA) is a granulomatous vasculitis affecting large arteries, especially the
aorta and the extracranial branches of the external carotid artery. Its exact pathogenesis is …

Objective To identify and validate, using computer‐driven methods, patterns of arterial
disease in Takayasu arteritis (TAK) and giant cell arteritis (GCA). Methods Patients with TAK …

The landscape of the investigation and management of giant cell arteritis (GCA) is
advancing. In this review we will outline the recent advances by searching the current …

The term “vasculitis” refers to a group of rare immune‐mediated diseases characterized by
the dysregulated immune system attacking blood vessels located in any organ of the body …

Autoimmune diseases can afflict every organ system, including blood vessels that are
critically important for host survival. The most frequent autoimmune vasculitis is giant cell …

Autoimmune and autoinflammatory diseases of the medium and large arteries, including the
aorta, cause life-threatening complications due to vessel wall destruction but also by wall …

Objectives Giant cell arteritis (GCA) is a complex systemic vasculitis mediated by the
interplay between both genetic and epigenetic factors. Monocytes are crucial players of the …