Genetics of obesity: what genetic association studies have taught us about the biology of obesity and its complications

MO Goodarzi - The lancet Diabetes & endocrinology, 2018 - thelancet.com
Genome-wide association studies (GWAS) for BMI, waist-to-hip ratio, and other adiposity
traits have identified more than 300 single-nucleotide polymorphisms (SNPs). Although …

Emotional eating and obesity in adults: the role of depression, sleep and genes

H Konttinen - Proceedings of the Nutrition Society, 2020 - cambridge.org
Stress and other negative emotions, such as depression and anxiety, can lead to both
decreased and increased food intake. The term 'emotional eating'has been widely used to …

Precision nutrition: a review of personalized nutritional approaches for the prevention and management of metabolic syndrome

J de Toro-Martín, BJ Arsenault, JP Després, MC Vohl - Nutrients, 2017 - mdpi.com
The translation of the growing increase of findings emerging from basic nutritional science
into meaningful and clinically relevant dietary advices represents nowadays one of the main …

The contribution of genetics and environment to obesity

D Albuquerque, C Nóbrega, L Manco… - British medical …, 2017 - academic.oup.com
Background Obesity is a global health problem mainly attributed to lifestyle changes such as
diet, low physical activity or socioeconomics factors. However, several evidences …

Is there a “metabolic-mood syndrome”? A review of the relationship between obesity and mood disorders

RB Mansur, E Brietzke, RS McIntyre - Neuroscience & Biobehavioral …, 2015 - Elsevier
Obesity and mood disorders are highly prevalent and co-morbid. Epidemiological studies
have highlighted the public health relevance of this association, insofar as both conditions …

Exposing the exposures responsible for type 2 diabetes and obesity

PW Franks, MI McCarthy - Science, 2016 - science.org
The rising prevalences of type 2 diabetes and obesity constitute major threats to human
health globally. Powerful social and economic factors influence the distribution of these …

Environment and gene association with obesity and their impact on neurodegenerative and neurodevelopmental diseases

MT Flores-Dorantes, YE Díaz-López… - Frontiers in …, 2020 - frontiersin.org
Obesity is a multifactorial disease in which environmental conditions and several genes play
an important role in the development of this disease. Obesity is associated with …

Current review of genetics of human obesity: from molecular mechanisms to an evolutionary perspective

D Albuquerque, E Stice, R Rodríguez-López… - Molecular genetics and …, 2015 - Springer
It is well-known that obesity is a complex multifactorial and heterogeneous condition with an
important genetic component. Recently, major advances in obesity research emerged …

Gene-diet interaction and precision nutrition in obesity

Y Heianza, L Qi - International journal of molecular sciences, 2017 - mdpi.com
The rapid rise of obesity during the past decades has coincided with a profound shift of our
living environment, including unhealthy dietary patterns, a sedentary lifestyle, and physical …

Gene–obesogenic environment interactions in the UK Biobank study

J Tyrrell, AR Wood, RM Ames… - International journal …, 2017 - academic.oup.com
Background: Previous studies have suggested that modern obesogenic environments
accentuate the genetic risk of obesity. However, these studies have proven controversial as …