Kallikrein-kinin system mediated inflammation in Alzheimer's disease in vivo

T A. Viel, H S. Buck - Current Alzheimer Research, 2011 - benthamdirect.com
The Kallikrein-Kinin System (KKS) has been associated to inflammatory and immunogenic
responses in the peripheral and central nervous system by the activation of two receptors …

Vagal afferent processing by the paratrigeminal nucleus

AK Driessen - Frontiers in physiology, 2019 - frontiersin.org
The paratrigeminal nucleus is an obscure region in the dorsal lateral medulla, which has
been best characterized as a collection of interstitial cells located in the dorsal tip of the …

Neuronal connections of the paratrigeminal nucleus: a topographic analysis of neurons projecting to bulbar, pontine and thalamic nuclei related to cardiovascular …

CA Caous, H de Sousa Buck, CJ Lindsey - Autonomic Neuroscience, 2001 - Elsevier
The paratrigeminal nucleus, which receives sensory input from trigeminal, glossopharyngeal
and vagus nerves, has efferent projections to bulbar, pontine and possibly to thalamic …

Projections of the paratrigeminal nucleus to the ambiguus, rostroventrolateral and lateral reticular nuclei, and the solitary tract

H de Sousa Buck, CA Caous, CJ Lindsey - Autonomic Neuroscience, 2001 - Elsevier
The paratrigeminal nucleus (Pa5), a constituent of the spinal interstitial system, was linked to
the pressor effect caused by bradykinin injected in the dorsal lateral medulla of the rat. The …

B2 bradykinin receptor immunoreactivity in rat brain

EY Chen, DF Emerich, RT Bartus… - Journal of …, 2000 - Wiley Online Library
Bradykinin has long been known to exist in the central nervous system and has been
hypothesized to mediate specific functions. Despite an increasing understanding of the …

Efferent and collateral organization of paratrigeminal nucleus projections: an anterograde and retrograde fluorescent tracer study in the rat

DW Saxon, DA Hopkins - Journal of Comparative Neurology, 1998 - Wiley Online Library
The paratrigeminal nucleus (PTN) receives primary visceral afferent projections through
cranial nerves IX and X and somatic afferent projections through cranial nerve V and dorsal …

Chapter VII Brain kallikrein–kinin system: from receptors to neuronal pathways and physiological functions

R Couture, CJ Lindsey - Handbook of chemical neuroanatomy, 2000 - Elsevier
Publisher Summary This chapter reviews substantial anatomical data describing the
distribution of bradykinin (BK) receptors as well as that of the biochemical machinery for the …

Increases of kinin B1 and B2 receptors binding sites after brain infusion of amyloid-beta 1–40 peptide in rats

TA Viel, AL Caetano, AG Nasello, CL Lancelotti… - Neurobiology of …, 2008 - Elsevier
Although numerous inflammation pathways have been implicated in Alzheimer's disease,
the involvement of the kallikrein–kinin system is still under investigation. We anatomically …

Reflex regulation of breathing by the paratrigeminal nucleus via multiple bulbar circuits

AK Driessen, MJ Farrell, M Dutschmann… - Brain Structure and …, 2018 - Springer
Sensory neurons of the jugular vagal ganglia innervate the respiratory tract and project to
the poorly studied medullary paratrigeminal nucleus. In the present study, we used …

Somatostatin in the rat rostral ventrolateral medulla: origins and mechanism of action

L Bou Farah, BR Bowman, P Bokiniec… - Journal of …, 2016 - Wiley Online Library
Somatostatin (SST) or agonists of the SST‐2 receptor (sst2) in the rostral ventrolateral
medulla (RVLM) lower sympathetic nerve activity, arterial pressure, and heart rate, or when …