[HTML][HTML] Astrocytes control recent and remote memory strength by affecting the recruitment of the CA1→ ACC projection to engrams
The maturation of engrams from recent to remote time points involves the recruitment of CA1
neurons projecting to the anterior cingulate cortex (CA1→ ACC). Modifications of G-protein …
neurons projecting to the anterior cingulate cortex (CA1→ ACC). Modifications of G-protein …
[HTML][HTML] Neuronal activation of Gαq EGL-30/GNAQ late in life rejuvenates cognition across species
ME Stevenson, G Bieri, R Kaletsky, JS Ange… - Cell reports, 2023 - cell.com
Loss of cognitive function with age is devastating. EGL-30/GNAQ and G αq signaling
pathways are highly conserved between C. elegans and mammals, and murine Gnaq is …
pathways are highly conserved between C. elegans and mammals, and murine Gnaq is …
Astrocytes in the Ventral Hippocampus Bidirectionally Regulate Innate and Stress‐Induced Anxiety‐Like Behaviors in Male Mice
JT Li, SY Jin, J Hu, RX Xu, JN Xu, ZM Li… - Advanced …, 2024 - Wiley Online Library
The mechanisms of anxiety disorders, the most common mental illness, remain incompletely
characterized. The ventral hippocampus (vHPC) is critical for the expression of anxiety …
characterized. The ventral hippocampus (vHPC) is critical for the expression of anxiety …
Chronic activation of a negative engram induces behavioral and cellular abnormalities
AL Jellinger, RL Suthard, B Yuan, M Surets, EA Ruesch… - Elife, 2024 - elifesciences.org
Negative memories engage a brain and body-wide stress response in humans that can alter
cognition and behavior. Prolonged stress responses induce maladaptive cellular, circuit …
cognition and behavior. Prolonged stress responses induce maladaptive cellular, circuit …
Spatial and single-cell transcriptomics reveal neuron-astrocyte interplay in long-term memory
Memory encodes past experiences, thereby enabling future plans. The basolateral
amygdala (BLA) is a center of salience networks that underlie emotional experience and …
amygdala (BLA) is a center of salience networks that underlie emotional experience and …
Neuronal Activation of the Gαq Protein EGL-30/GNAQ Late in Life Rejuvenates Cognition Across Species
ME Stevenson, G Bieri, R Kaletsky, JS Ange… - bioRxiv, 2023 - biorxiv.org
Cognitive decline is perhaps the most devastating aging loss. EGL-30/GNAQ and Gαq
signaling pathways are highly conserved between C. elegans and mammals. We find that …
signaling pathways are highly conserved between C. elegans and mammals. We find that …
[PDF][PDF] Activation of the hippocampal CA1 astrocyte Gq and Gi G protein-coupled receptors exerts a protective effect against attention deficit hyperactivity disorder
YD Shan, ZF Yu, GG Lv, YL Shan, BD Li, JY Zhao… - 2024 - scholar.archive.org
Background Attention de cit hyperactivity disorder (ADHD) is characterized by symptoms
such as inattention, hyperactivity and impulsiveness, which signi cantly impact the healthy …
such as inattention, hyperactivity and impulsiveness, which signi cantly impact the healthy …