[HTML][HTML] Natural antioxidants improve the vulnerability of cardiomyocytes and vascular endothelial cells under stress conditions: a focus on mitochondrial quality …

X Chang, Z Zhao, W Zhang, D Liu, C Ma… - … Medicine and Cellular …, 2021 - ncbi.nlm.nih.gov
Cardiovascular disease has become one of the main causes of human death. In addition,
many cardiovascular diseases are accompanied by a series of irreversible damages that …

Heart Disease and Microgravity: The Dawn of a New Medical Era?: A Narrative Review

O Giacinto, ML Garo, F Pelliccia, A Minati… - Cardiology in …, 2023 - journals.lww.com
After a decline in interest in space missions following the cessation of the Apollo missions,
there has been a recent resurgence. Activities on the International Space Station have …

[HTML][HTML] Surfactin alleviated hyperglycaemia in mice with type 2 diabetes induced by a high-fat diet and streptozotocin

X Chen, H Zhao, F Meng, L Zhou, Z Lu, Y Lu - Food Science and Human …, 2023 - Elsevier
Type 2 diabetes mellitus (T2DM) is associated with liver dysfunction and intestinal dysbiosis.
Bioactive peptides (BAPs) have been reported to ameliorate T2DM by preventing oxidative …

The coupling of reduced type H vessels with unloading-induced bone loss and the protection role of Panax quinquefolium saponin in the male mice

S Liang, S Ling, R Du, Y Li, C Liu, J Shi, J Gao, W Sun… - Bone, 2021 - Elsevier
Unloading-induced bone loss is a critical complication characterized by the imbalance of
bone formation and resorption induced by long-term confinement in bed or spaceflight …

Panax Quinquefolium Saponins enhances angiogenesis in rats with diabetes and myocardial infarction

D Pan, L Xu, P Chen, L Miao, Y Tian, D Shi… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Xi Yang Shen (Panax quinquefolium L.) was
originally recorded in “Ben Cao Cong Xin” edited by Wu Yiluo during the Qing Dynasty …

Comprehensive Lipidome and Metabolome Profiling Investigations of Panax quinquefolius and Application in Different Growing Regions Using Liquid …

L Li, D Wang, C Sun, Y Li, H Lu… - Journal of Agricultural and …, 2021 - ACS Publications
Panax quinquefolius is one of the most recognized ginseng species. In this study, lipidome
and metabolome extraction methods for P. quinquefolius were optimized with …

LncRNA AC061961. 2 overexpression inhibited endoplasmic reticulum stress induced apoptosis in dilated cardiomyopathy rats and cardiomyocytes via activating wnt …

Z Qiu, W Chen, Y Liu, B Jiang, L Yin… - Journal of Receptors and …, 2021 - Taylor & Francis
Abstract Down-regulated lncRNA AC061961. 2 in dilated cardiomyopathy (DCM) patients
was previous reported. Whether AC061961. 2 has regulatory effect on DCM still need …

Panax quinquefolius saponins and panax notoginseng saponins attenuate myocardial hypoxia-reoxygenation injury by reducing excessive mitophagy

J Xia, C Chen, Y Sun, S Li, Y Li, BR Cheng… - Cell Biochemistry and …, 2024 - Springer
Objective Panax quinquefolius saponins (PQS) and Panax notoginseng saponins (PNS) are
key bioactive compounds in Panax quinquefolius L. and Panax notoginseng, commonly …

Loss and recovery of myocardial mitochondria in mice under different tail suspension time: Apoptosis and mitochondrial fission, fusion and autophagy

Z Wang, XC Wang, YF Chen, CL Wang… - Experimental …, 2023 - Wiley Online Library
Long‐term weightlessness in animals can cause changes in myocardial structure and
function, in which mitochondria play an important role. Here, a tail suspension (TS) Kunming …

Hawthorn leaves flavonoids attenuate cardiac remodeling induced by simulated microgravity

T Liu, Y Ma, H Zhao, P Wang, Y Niu, Y Hu… - Pharmaceutical …, 2023 - Taylor & Francis
Context Hawthorn leaves are a kind of widely used medicinal plant in China. The major
ingredient, hawthorn leaves flavonoids (HLF), have cardiotonic, cardioprotective, and …