Are reactive oxygen species involved in Alzheimer's disease?

G Benzi, A Moretti - Neurobiology of aging, 1995 - Elsevier
Alzheimer's disease has a multifactorial pathogenesis. Among the various factors involved,
this review examines, in particular, the possibility of oxidative stress, meaning an imbalance …

Age-and peroxidative stress-related modifications of the cerebral enzymatic activities linked to mitochondria and the glutathione system

G Benzi, A Moretti - Free Radical Biology and Medicine, 1995 - Elsevier
The aging brain undergoes a process of enhanced peroxidative stress, as shown by reports
of altered membrane lipids, oxidized proteins, and damaged DNA. The aims of this review …

In Vitro and In Vivo Antioxidant Activity of Bifidobacterium animalis 01 Isolated from Centenarians

Q Shen, N Shang, P Li - Current microbiology, 2011 - Springer
Several studies reported the antioxidant activity of bifidobacteria using assays in vitro. In
present study, the in vitro and in vivo antioxidant activity of Bifidobacterium animalis 01 was …

Neuroprotective and anti-ageing effects of curcumin in aged rat brain regions

K Bala, BC Tripathy, D Sharma - Biogerontology, 2006 - Springer
This study investigated the influence of chronically administered curcumin on normal ageing-
related parameters: lipid peroxidation, lipofuscin concentration and intraneuronal lipofuscin …

In vitro and in vivo antioxidant activity of exopolysaccharide fractions from Bifidobacterium animalis RH

R Xu, N Shang, P Li - Anaerobe, 2011 - Elsevier
The aim of the study was to purify the exopolysaccharides (EPS) produced from
Bifidobacterium animalis RH, which was isolated from the feces of Bama centenarians in …

The Neuroprotective Effect of Curcumin and Nigella sativa Oil Against Oxidative Stress in the Pilocarpine Model of Epilepsy: A Comparison with Valproate

HS Aboul Ezz, YA Khadrawy, NA Noor - Neurochemical research, 2011 - Springer
Oxidative stress has been implicated to play a role in epileptogenesis and pilocarpine-
induced seizures. The present study aims to evaluate the antioxidant effects of curcumin …

Redox signaling in neurotransmission and cognition during aging

A Kumar, B Yegla, TC Foster - Antioxidants & Redox Signaling, 2018 - liebertpub.com
Significance: Oxidative stress increases in the brain with aging and neurodegenerative
diseases. Previous work emphasized irreversible oxidative damage in relation to cognitive …

Studies on lipid peroxidation and protein oxidation in the aging brain

M Cini, A Moretti - Neurobiology of aging, 1995 - Elsevier
Lipid peroxidation (LP) and protein oxidation (PO) were investigated in hippocampus and
frontal cortex homogenates from young (5 months), mature (13 months) and old (24 months) …

Aluminium-induced electrophysiological, biochemical and cognitive modifications in the hippocampus of aging rats

P Sethi, A Jyoti, R Singh, E Hussain, D Sharma - Neurotoxicology, 2008 - Elsevier
Aluminium (Al) is the most abundant metal known for its neurotoxicity in humans. It gains
easy access to the central nervous system under normal physiological conditions and …

A metabolic and functional overview of brain aging linked to neurological disorders

NZ Baquer, A Taha, P Kumar, P McLean, SM Cowsik… - Biogerontology, 2009 - Springer
Close correlations have recently been shown among the late onset complications
encountered in diabetes and aging linked to neurobiological disorders. Aging in females …