The urogenital tract is a complex environment composed of many different types of epithelial
tissues and innate immune cells that sample the surrounding milieu. As a host-adapted …

The bacterium Neisseria gonorrhoeae causes the sexually transmitted infection (STI)
gonorrhoea, which has an estimated global annual incidence of 86.9 million adults …

Bacterial pathogens employ a number of genetic strategies to cause infection and,
occasionally, disease in their hosts. Many of these virulence factors and their regulatory …

Phase and antigenic variation result in a heterogenic phenotype of a clonal bacterial
population, in which individual cells either express the phase-variable protein (s) or not, or …

Neisseria gonorrhoeae is a common sexually transmitted pathogen that significantly impacts
female fertility, neonatal health, and transmission of HIV worldwide. N. gonorrhoeae usually …

Infection with Neisseria gonorrhoeae can trigger an intense inflammatory response, yet
there is little specific immune response or development of immune memory. In addition …

▪ Abstract The closely related bacterial pathogens Neisseria gonorrhoeae (gonococci, GC)
and N. meningitidis (meningococci, MC) initiate infection at human mucosal epithelia …

Neisseria gonorrheoae is the causative agent of gonorrhea, a sexually transmitted infection
responsible for a major burden of disease with a high global prevalence. Protective …

Neisseria gonorrhoeae (also known as gonococcus) has been causing gonorrhoea in
humans since ancient Egyptian times. Today, global gonorrhoea infections are rising at an …

The development of effective prophylactic agents against gonorrhea and the study of
adaptation by Neisseria gonorrhoeae to the urogenital mucosa are hindered by the lack of a …