The therapeutic journey of benzimidazoles: A review

Y Bansal, O Silakari - Bioorganic & medicinal chemistry, 2012 - Elsevier
Presence of benzimidazole nucleus in numerous categories of therapeutic agents such as
antimicrobials, antivirals, antiparasites, anticancer, anti-inflammatory, antioxidants, proton …

Structure–activity relationship analysis of benzimidazoles as emerging anti-inflammatory agents: An overview

R Veerasamy, A Roy, R Karunakaran, H Rajak - Pharmaceuticals, 2021 - mdpi.com
A significant number of the anti-inflammatory drugs currently in use are becoming obsolete.
These are exceptionally hazardous for long-term use because of their possible unfavourable …

Computational repurposing of benzimidazole anthelmintic drugs as potential colchicine binding site inhibitors

M Khattab, AA Al-Karmalawy - Future Medicinal Chemistry, 2021 - Taylor & Francis
Background: Although some benzimidazole-based anthelmintic drugs are found to possess
anticancer activity, their modes of binding interactions have not been reported. Methodology …

Revisiting activity of some nocodazole analogues as a potential anticancer drugs using molecular docking and DFT calculations

M Khattab, AA Al‐Karmalawy - Frontiers in Chemistry, 2021 - frontiersin.org
Although potential anticancer activities of benzimidazole-based anthelmintic drugs have
been approved by preclinical and clinical studies, modes of binding interactions have not …

Design, synthesis and biological evaluation of 1, 3-diphenyl-1H-pyrazole derivatives containing benzimidazole skeleton as potential anticancer and apoptosis …

TS Reddy, H Kulhari, VG Reddy, V Bansal… - European journal of …, 2015 - Elsevier
A series of forty different pyrazole containing benzimidazole hybrids (6–45) have been
designed, synthesized and evaluated for their potential anti-proliferative activity against …

Recent developments in azole compounds as antibacterial and antifungal agents

XM Peng, GX Cai, CH Zhou - Current Topics in Medicinal …, 2013 - ingentaconnect.com
Azole compounds are an important class of nitrogen heterocycles with electron-rich
property. This special structure endows azole-based derivatives easily bind with the …

A review on the green synthesis of benzimidazole derivatives and their pharmacological activities

M Nardi, NCH Cano, S Simeonov, R Bence, A Kurutos… - Catalysts, 2023 - mdpi.com
Benzimidazoles and their derivatives play an extraordinarily significant role as therapeutic
agents, eg, antiulcer, analgesic, and anthelmintic drugs. The organic synthesis of …

[HTML][HTML] Synthesis and characterization of different complexes derived from Schiff base and evaluation as a potential anticancer, antimicrobial, and insecticide agent

LM Aroua, SK Alhag, LA Al-Shuraym… - Saudi Journal of …, 2023 - Elsevier
The condensation of (1H-benzimidazole-2-yl) methanamine, with 2-hydroxy
naphthaldehyde lead to Schiff base ligand (H2L)(1). This was later reacted with metal salts …

A versatile approach to Ullmann C–N couplings at room temperature: New families of nucleophiles and electrophiles for photoinduced, copper-catalyzed processes

DT Ziegler, J Choi, JM Muñoz-Molina… - Journal of the …, 2013 - ACS Publications
The use of light to facilitate copper-catalyzed cross-couplings of nitrogen nucleophiles can
enable C–N bond formation to occur under unusually mild conditions. In this study, we …

Plasmon induced hot electron generation in two dimensional carbonaceous nanosheets decorated with Au nanostars: enhanced photocatalytic activity under visible …

A Kumar, P Choudhary, K Kumar, A Kumar… - Materials Chemistry …, 2021 - pubs.rsc.org
Rational design and development of photocatalytic materials is of paramount importance for
efficient utilization of solar energy in photocatalytic applications. The conventional …