Pathogenesis of allergic diseases and implications for therapeutic interventions

J Wang, Y Zhou, H Zhang, L Hu, J Liu, L Wang… - Signal transduction and …, 2023 - nature.com
Allergic diseases such as allergic rhinitis (AR), allergic asthma (AAS), atopic dermatitis (AD),
food allergy (FA), and eczema are systemic diseases caused by an impaired immune …

Immunology of food allergy

L Tordesillas, MC Berin, HA Sampson - Immunity, 2017 - cell.com
Many consider food allergy as the" second wave" of the allergy epidemic following the" first
wave" of respiratory allergy, ie, asthma and allergic rhinitis, plaguing westernized countries …

A consensus approach to the primary prevention of food allergy through nutrition: guidance from the American Academy of Allergy, Asthma, and Immunology; …

DM Fleischer, ES Chan, C Venter, JM Spergel… - The Journal of Allergy …, 2021 - Elsevier
Recently published data from high-impact randomized controlled trials indicate the strong
potential of strategies to prevent the development of food allergy in high-risk individuals, but …

Filaggrin mutations associated with skin and allergic diseases

AD Irvine, WHI McLean… - New England Journal of …, 2011 - Mass Medical Soc
Filaggrin Mutations Associated with Skin and Allergic Diseases | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Role of the intestinal epithelium and its interaction with the microbiota in food allergy

A Ali, HY Tan, GE Kaiko - Frontiers in Immunology, 2020 - frontiersin.org
The intestinal epithelial tract forms a dynamic lining of the digestive system consisting of a
range of epithelial cell sub-types with diverse functions fulfilling specific niches. The …

Update on risk factors for food allergy

G Lack - Journal of Allergy and Clinical Immunology, 2012 - Elsevier
Despite efforts to prevent food allergy (FA) in children, IgE-mediated FAs are increasing in
westernized countries. Previous preventive strategies, such as prolonged exclusive breast …

Update on food allergy

HA Sampson - Journal of allergy and clinical immunology, 2004 - Elsevier
Tremendous progress has been made in our understanding of food-based allergic disorders
over the past 5 years. Recent epidemiologic studies suggest that nearly 4% of Americans …

Early‐life gut microbiome and egg allergy

M Fazlollahi, Y Chun, A Grishin, RA Wood, AW Burks… - Allergy, 2018 - Wiley Online Library
Background Gut microbiota may play a role in egg allergy. We sought to examine the
association between early‐life gut microbiota and egg allergy. Methods We studied 141 …

[HTML][HTML] Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy

SJ Brown, Y Asai, HJ Cordell, LE Campbell… - Journal of allergy and …, 2011 - Elsevier
BACKGROUND: IgE-mediated peanut allergy is a complex trait with strong heritability, but its
genetic basis is currently unknown. Loss-of-function mutations within the filaggrin gene are …

Epidemiologic risks for food allergy

G Lack - Journal of Allergy and Clinical Immunology, 2008 - Elsevier
This article reviews possible risk factors and theories for the development of food allergy. It is
noted that previous strategies to prevent food allergy through allergen avoidance during …