The brain harbors a unique ability to, figuratively speaking, shift its gears. During
wakefulness, the brain is geared fully toward processing information and behaving, while …

Endothelial cells (ECs) are more than inert blood vessel lining material. Instead, they are
active players in the formation of new blood vessels (angiogenesis) both in health and (life …

Tunable gating graphene oxide (GO) membranes with high water permeance and precise
molecular separation remain highly desired in smart nanofiltration devices. Herein …

The glycocalyx is a polysaccharide structure that protrudes from the body of a cell. It is
primarily conformed of glycoproteins and proteoglycans, which provide communication …

Chronic kidney disease (CKD) represents a leading cause of death in the United States.
There is no cure for this disease, with current treatment strategies relying on blood pressure …

In this work we model the glomerular filtration barrier, the structure responsible for filtering
the blood and preventing the loss of proteins, using human podocytes and glomerular …

Stenting is currently the major therapeutic treatment for cardiovascular diseases. However,
the nonbiogenic metal stents are inclined to trigger a cascade of cellular and molecular …

Dysfunctional endothelial cells are an essential contributor to the progression of diverse
chronic cardiovascular, renal, and metabolic diseases. It manifests in impairment of nitric …

The endothelial glycocalyx is a vital regulator of vascular permeability. Damage to this
delicate layer can result in increased protein and water transit. The clinical importance of …

Glomerular endothelial cell (GEnC) dysfunction is important in the pathogenesis of
glomerular sclerotic diseases, including Focal Segmental Glomerulosclerosis (FSGS) and …