As a nontraditional T-cell subgroup, γδT cells have gained popularity in the field of
immunotherapy in recent years. They have extraordinary antitumor potential and prospects …

Common variable immunodeficiency (CVID) is a heterogeneous disorder characterized by
hypogammaglobulinemia and increased susceptibility to recurrent bacterial infections. It is …

Increasing immunological knowledge and advances in techniques lay the ground for more
efficient and broader application of immunotherapies. gamma delta (γδ) T-cells possess …

Congenital Zika syndrome (CZS) causes early brain development impairment by affecting
neural progenitor cells (NPCs). Here, we analyze NPCs from three pairs of dizygotic twins …

Gamma delta (γδ) T-cell based immunotherapy is a promising concept for the treatment of
hematologic malignancies. Not only in vitro but also in early phase clinical trials, zoledronic …

The function and phenotype of γδ T cells in the context of common variable
immunodeficiency (CVID) has not been explored. CVID is a primary immunodeficiency …

T lymphocytes are the key protective contributors in chronic infection and tumor, but
experience exhaustion by persistent antigen stimulation. As an unconventional lineage of T …

Recently, many discoveries have elucidated the cellular and molecular diversity in the
leukemic microenvironment and improved our knowledge regarding their complex nature …

Common variable immunodeficiency (CVID) is one of the inborn errors of immunity that have
the greatest clinical impact. Rates of morbidity and mortality are higher in patients with CVID …

Abstract Common Variable Immunodeficiency (CVID) is a primary immunodeficiency
characterized by reduced levels of specific immunoglobulins, resulting in frequent infections …