Immunosuppressive agents and infectious risk in transplantation: managing the “net state of immunosuppression”

MB Roberts, JA Fishman - Clinical Infectious Diseases, 2021 - academic.oup.com
Successful solid organ transplantation reflects meticulous attention to the details of
immunosuppression, balancing risks for graft rejection against risks for infection. The “net …

Cytomegalovirus vaccines: current status and future prospects

KM Anderholm, CJ Bierle, MR Schleiss - Drugs, 2016 - Springer
Congenital human cytomegalovirus (HCMV) infection can result in severe and permanent
neurological injury in newborns, and vaccine development is accordingly a major public …

[HTML][HTML] Reduced incidence of cytomegalovirus infection in kidney transplant recipients receiving everolimus and reduced tacrolimus doses

H Tedesco-Silva, C Felipe, A Ferreira, M Cristelli… - American Journal of …, 2015 - Elsevier
This study compared the incidence of CMV infection/disease in de novo kidney transplant
recipients receiving everolimus or mycophenolate and no CMV pharmacological …

[HTML][HTML] Common viral infections in kidney transplant recipients

J Vanichanan, S Udomkarnjananun… - Kidney research and …, 2018 - ncbi.nlm.nih.gov
Infectious complications have been considered as a major cause of morbidity and mortality
after kidney transplantation, especially in the Asian population. Therefore, prevention, early …

New therapies for human cytomegalovirus infections

WJ Britt, MN Prichard - Antiviral research, 2018 - Elsevier
The recent approval of letermovir marks a new era of therapy for human cytomegalovirus
(HCMV) infections, particularly for the prevention of HCMV disease in hematopoietic stem …

Unmasking the tissue-resident eukaryotic DNA virome in humans

L Pyöriä, D Pratas, M Toppinen, K Hedman… - Nucleic Acids …, 2023 - academic.oup.com
Little is known on the landscape of viruses that reside within our cells, nor on the interplay
with the host imperative for their persistence. Yet, a lifetime of interactions conceivably have …

Cytomegalovirus therapy: role of letermovir in prophylaxis and treatment in transplant recipients

JL Saullo, RA Miller - Annual Review of Medicine, 2023 - annualreviews.org
Cytomegalovirus (CMV) is a common viral pathogen in the transplant population and is
associated with significant morbidity and mortality. CMV prevention is paramount; however …

[HTML][HTML] Cytomegalovirus mismatch still negatively affects patient and graft survival in the era of routine prophylactic and preemptive therapy: a paired kidney analysis

N Leeaphorn, N Garg, N Thamcharoen… - American Journal of …, 2019 - Elsevier
The impact of cytomegalovirus (CMV) serostatus on kidney transplant outcomes in an era
when CMV prophylactic and preemptive strategies are used routinely is not clearly …

Management of cytomegalovirus infection in solid organ transplant recipients: SET/GESITRA-SEIMC/REIPI recommendations

J Torre-Cisneros, JM Aguado, JJ Caston… - Transplantation …, 2016 - Elsevier
Cytomegalovirus (CMV) infection remains a major complication of solid organ
transplantation. Because of management of CMV is variable among transplant centers, in …

Polyfunctional T-cell signatures to predict protection from cytomegalovirus after lung transplantation

LD Snyder, C Chan, D Kwon, JS Yi… - American Journal of …, 2016 - atsjournals.org
Rationale: Cytomegalovirus (CMV), which is one of the most common infections after lung
transplantation, is associated with chronic lung allograft dysfunction and worse post …