Molecular mechanisms of parthanatos and its role in diverse diseases
P Huang, G Chen, W Jin, K Mao, H Wan… - International journal of …, 2022 - mdpi.com
Differential evolution of apoptosis, programmed necrosis, and autophagy, parthanatos is a
form of cell death mediated by poly (ADP-ribose) polymerase 1 (PARP1), which is caused by …
form of cell death mediated by poly (ADP-ribose) polymerase 1 (PARP1), which is caused by …
[HTML][HTML] PARPs in lipid metabolism and related diseases
PARPs and tankyrases (TNKS) represent a family of 17 proteins. PARPs and tankyrases
were originally identified as DNA repair factors, nevertheless, recent advances have shed …
were originally identified as DNA repair factors, nevertheless, recent advances have shed …
Spatiotemporal roles of AMPK in PARP-1-and autophagy-dependent retinal pigment epithelial cell death caused by UVA
Background Although stimulating autophagy caused by UV has been widely demonstrated
in skin cells to exert cell protection, it remains unknown the cellular events in UVA-treated …
in skin cells to exert cell protection, it remains unknown the cellular events in UVA-treated …
[HTML][HTML] Role of mitochondria on UV-induced skin damage and molecular mechanisms of active chemical compounds targeting mitochondria
H He, L Xiong, L Jian, L Li, Y Wu, S Qiao - Journal of Photochemistry and …, 2022 - Elsevier
Mitochondria are the principal place of energy metabolism and ROS production, leading to
mtDNA being especially sensitive to the impacts of oxidative stress. Our review aims to …
mtDNA being especially sensitive to the impacts of oxidative stress. Our review aims to …
Potential Use of Amla (Phyllanthus emblica L.) Fruit Extract to Protect Skin Keratinocytes from Inflammation and Apoptosis after UVB Irradiation
K Kunchana, W Jarisarapurin, L Chularojmontri… - Antioxidants, 2021 - mdpi.com
Ultraviolet B (UVB) exposure is the primary risk factor for the deadliest type of skin cancer—
melanoma. Incorporating natural antioxidants in skin protection products is currently a …
melanoma. Incorporating natural antioxidants in skin protection products is currently a …
Role of PARP-1 in mitochondrial homeostasis
Background Nuclear poly (ADP-ribose) polymerase-1 (PARP-1) is a well characterised
protein that accounts for the majority of PARylation reactions using NAD+ as a substrate …
protein that accounts for the majority of PARylation reactions using NAD+ as a substrate …
Ergothioneine alleviates senescence of fibroblasts induced by UVB damage of keratinocytes via activation of the Nrf2/HO-1 pathway and HSP70 in keratinocytes
HJ Ko, J Kim, M Ahn, JH Kim, GS Lee, T Shin - Experimental Cell Research, 2021 - Elsevier
Ultraviolet B (UVB) irradiation induces skin damage and photoaging through several
deleterious effects, including generation of reactive oxygen species (ROS), apoptosis of …
deleterious effects, including generation of reactive oxygen species (ROS), apoptosis of …
Mitochondrial quality control and metabolic memory phenomenon associated with continued progression of diabetic retinopathy
RA Kowluru, K Alka - International Journal of Molecular Sciences, 2023 - mdpi.com
Diabetic retinopathy continues to progress even when hyperglycemia is terminated,
suggesting a 'metabolic memory'phenomenon. Mitochondrial dysfunction is closely …
suggesting a 'metabolic memory'phenomenon. Mitochondrial dysfunction is closely …
Impaired mitophagy causes mitochondrial DNA leakage and STING activation in ultraviolet B-irradiated human keratinocytes HaCaT
C Li, Y Zhu, W Liu, W Xiang, S He, T Hayashi… - Archives of Biochemistry …, 2023 - Elsevier
Ultraviolet B (UVB) irradiation causes skin damages. In this study, we focus on the
involvement of mitochondrial disorders in UVB injury. Surprisingly, UVB irradiation increases …
involvement of mitochondrial disorders in UVB injury. Surprisingly, UVB irradiation increases …
[HTML][HTML] Cyclobutane pyrimidine dimers from UVB exposure induce a hypermetabolic state in keratinocytes via mitochondrial oxidative stress
Ultraviolet B radiation (UVB) is an environmental complete carcinogen, which induces and
promotes keratinocyte carcinomas, the most common human malignancies. UVB induces …
promotes keratinocyte carcinomas, the most common human malignancies. UVB induces …