[PDF][PDF] Temporal correlations robustly reveal regulatory coherence upon environmental perturbation

H Cai, DL Des Marais - bioRxiv, 2021 - scholar.archive.org
Transcriptional regulation plays a fundamental role in the behavior of cells responding to
external 21 and internal environmental cues, and is aberrant in many diseases (Lee and …

Revisiting regulatory decoherence and phenotypic integration: accounting for temporal bias in co-expression analyses

H Cai, DL Des Marais - bioRxiv, 2021 - biorxiv.org
Environment can alter the degree of phenotypic variation and covariation, potentially
influencing evolutionary trajectories. However, environment-driven changes in phenotypic …

[PDF][PDF] Revisiting regulatory decoherence: Accounting for temporal bias in a co-expression analysis reveals novel candidates controlling environmental response

H Cai, D Des Marais - 2022 - academia.edu
Transcriptional Regulatory Networks (TRNs) orchestrate the timing, magnitude, and rate 2 of
organismal response to many environmental perturbations. Regulatory interactions 3 in …