HIV subtype diversity worldwide
N Bbosa, P Kaleebu, D Ssemwanga - Current Opinion in HIV and …, 2019 - journals.lww.com
The dynamic change in HIV subtype distribution presents future challenges for diagnosis,
treatment and vaccine design and development. An increase in recombinant viruses …
treatment and vaccine design and development. An increase in recombinant viruses …
Genetic cluster analysis for HIV prevention
Abstract Purpose of Review This review summarizes the use of genetic similarity clusters to
understand HIV transmission and inform prevention efforts. Recent Findings Recent …
understand HIV transmission and inform prevention efforts. Recent Findings Recent …
Quantifying HIV transmission flow between high-prevalence hotspots and surrounding communities: a population-based study in Rakai, Uganda
Background International and global organisations advocate targeting interventions to areas
of high HIV prevalence (ie, hotspots). To better understand the potential benefits of geo …
of high HIV prevalence (ie, hotspots). To better understand the potential benefits of geo …
A comprehensive genomics solution for HIV surveillance and clinical monitoring in low-income settings
Viral genetic sequencing can be used to monitor the spread of HIV drug resistance, identify
appropriate antiretroviral regimes, and characterize transmission dynamics. Despite …
appropriate antiretroviral regimes, and characterize transmission dynamics. Despite …
Easy and accurate reconstruction of whole HIV genomes from short-read sequence data with shiver
Studying the evolution of viruses and their molecular epidemiology relies on accurate viral
sequence data, so that small differences between similar viruses can be meaningfully …
sequence data, so that small differences between similar viruses can be meaningfully …
Inferring HIV-1 transmission networks and sources of epidemic spread in Africa with deep-sequence phylogenetic analysis
To prevent new infections with human immunodeficiency virus type 1 (HIV-1) in sub-
Saharan Africa, UNAIDS recommends targeting interventions to populations that are at high …
Saharan Africa, UNAIDS recommends targeting interventions to populations that are at high …
Longitudinal population-level HIV epidemiologic and genomic surveillance highlights growing gender disparity of HIV transmission in Uganda
HIV incidence in eastern and southern Africa has historically been concentrated among girls
and women aged 15–24 years. As new cases decline with HIV interventions, population …
and women aged 15–24 years. As new cases decline with HIV interventions, population …
Growing gender disparity in HIV infection in Africa: sources and policy implications
HIV incidence in eastern and southern Africa has historically been concentrated among girls
and women aged 15-24 years, but as new cases decline with HIV interventions, population …
and women aged 15-24 years, but as new cases decline with HIV interventions, population …
Effect of HIV subtype and antiretroviral therapy on HIV-associated neurocognitive disorder stage in Rakai, Uganda
N Sacktor, D Saylor, G Nakigozi… - JAIDS Journal of …, 2019 - journals.lww.com
Background: Combination antiretroviral therapy (ART) improves HIV-associated
neurocognitive disorder (HAND) stage in the United States where subtype B predominates …
neurocognitive disorder (HAND) stage in the United States where subtype B predominates …
Empirical comparison of analytical approaches for identifying molecular HIV-1 clusters
Public health interventions guided by clustering of HIV-1 molecular sequences may be
impacted by choices of analytical approaches. We identified commonly-used clustering …
impacted by choices of analytical approaches. We identified commonly-used clustering …