MicroRNAs and their influence on the ZEB family: mechanistic aspects and therapeutic applications in cancer therapy

M Ashrafizadeh, HL Ang, ER Moghadam… - Biomolecules, 2020 - mdpi.com
Molecular signaling pathways involved in cancer have been intensively studied due to their
crucial role in cancer cell growth and dissemination. Among them, zinc finger E-box binding …

The impact of non-coding RNAs in the epithelial to mesenchymal transition

BM Hussen, H Shoorei, M Mohaqiq… - Frontiers in molecular …, 2021 - frontiersin.org
Epithelial to mesenchymal transition (EMT) is a course of action that enables a polarized
epithelial cell to undertake numerous biochemical alterations that allow it to adopt features …

A computational systems biology approach identifies SLUG as a mediator of partial Epithelial-Mesenchymal Transition (EMT)

AR Subbalakshmi, S Sahoo, K Biswas, MK Jolly - Cells Tissues Organs, 2022 - karger.com
Epithelial-mesenchymal plasticity comprises reversible transitions among epithelial, hybrid
epithelial/mesenchymal (E/M) and mesenchymal phenotypes, and underlies various aspects …

Non-coding RNAs set a new phenotypic frontier in prostate cancer metastasis and resistance

J Altschuler, JA Stockert, N Kyprianou - International Journal of Molecular …, 2021 - mdpi.com
Prostate cancer (PCa) mortality remains a significant public health problem, as advanced
disease has poor survivability due to the development of resistance in response to both …

The potential of microRNAs as non-invasive prostate cancer biomarkers: A systematic literature review based on a machine learning approach

E Bevacqua, S Ammirato, E Cione, R Curcio, V Dolce… - Cancers, 2022 - mdpi.com
Simple Summary Prostate cancer (PCa) is the most common cancer in men worldwide.
Screening and diagnosis are based on prostate-specific antigen (PSA) blood testing and …

Construction of potential gene expression and regulation networks in prostate cancer using bioinformatics tools

H Liu, L Li, Y Fan, Y Lu, C Zhu… - Oxidative medicine and …, 2021 - Wiley Online Library
Objective. To identify the key genes involved in prostate cancer and their regulatory network.
Methods. The dataset of mRNA/miRNA transcriptome sequencing was downloaded from …

Mitochondrial proteome analysis reveals that an augmented cytochrome c oxidase assembly and activity potentiates respiratory capacity in sarcoma

M Bedi, S Das, J Das, S Mukherjee, A Basu… - Biochemical and …, 2024 - Elsevier
Mitochondrial oxidative phosphorylation (OXPHOS) is an obligatory process in sarcoma.
Despite that, the metabolic programming of sarcoma mitochondria is still unknown. To obtain …

CCNDBP1, a Prognostic Marker Regulated by DNA Methylation, Inhibits Aggressive Behavior in Dedifferentiated Liposarcoma via Repressing Epithelial …

L Yang, Z Wu, W Sun, P Luo, S Chen, Y Chen… - Frontiers in …, 2021 - frontiersin.org
The present study aimed to explore the prognostic value, function, and mechanism of
CCNDBP1 in dedifferentiated liposarcoma (DDL). Immunohistochemistry staining was used …

[Retracted] MiR‐373 Inhibits the Epithelial‐Mesenchymal Transition of Prostatic Cancer via Targeting Runt‐Related Transcription Factor 2

J Pang, L Dai, C Zhang, Q Zhang - Journal of Healthcare …, 2021 - Wiley Online Library
Prostatic cancer (PCa) is a prevalent form of malignancy based on its high associated levels
of mortality and morbidity across the world. MicroRNAs (miRNAs) are significant in the …

Role of IGF2 in the Study of Development and Evolution of Prostate Cancer

P Porras-Quesada, JM González-Cabezuelo… - Frontiers in …, 2022 - frontiersin.org
Prostate Cancer (PC) is commonly known as one of the most frequent tumors among males.
A significant problem of this tumor is that in early stages most of the cases course as indolent …